Online ISSN: 2515-8260

Keywords : diastolic blood pressure


A Study of Serum Ferritin in Metabolic Syndrome

Gorijala Aparna, Uppalapati Ganga Prasad, Veluguri Aravind

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 6031-6044

Background:The present study was done to determine the association of serum Ferritin
in Metabolic Syndrome as well as to determine the relation between individual
component of metabolic syndrome and number of components metabolic syndrome and
plasma ferritin.
Materials and Methods: It was a Cross-sectional study. The study was carried out at
NRI Medical College & Hospital, CHINAKAKANI, GUNTUR. The study was included
Metabolic syndrome patients diagnosed as per NCEP (National Cholesterol Education
Program) ATP III (Adult Treatment Panel III) (2001) attending the NRI medical
college and Hospital during the study period from March 2021 to March 2022. It is a
Correlational clinical single group study with 102 patients.
Results: In the present study, the mean age group of the study population was 57.38
±8.05. The majority of the study participants belonged to the 51–60 years age group, i.e.,
40.2%, followed by 36.3% in 61–70 years age group. In the present study, the majority
of the study population were male, i.e., 62.7% and females were 37.3%. In the present
study, the majority of the male and female belonged to 51- 70 years age group. In the
present study, overweight was 42%, and obese was 58%. In the present study, the
majority, i.e., 98.4%, had a waist circumference of >90 cm, and among the female
majority, i.e., 94.7% had a waist circumference of >85cm. In the present study, 87.3%
had systolic Blood pressure >130 mmHg, and 84.3% had Diastolic Blood pressure >85
mmHg. In the present study, 62.7% were Hypertensives and were taking regular
medications. 78.4% of the study population were diabetics. The mean duration of
diabetes in the present study was 2.11 ± 0.84. 18.6% had a duration of diabetes <3 years,
3-6 years in 37.3%, and 22.5% had a period being >6 years. 22.5% had 1+ urine
albumin, 2.9% with 2+ urine albumin. 74.5% didn’t show any albumin in urine
analysis. 61.8% had no sugar in the urine. Trances of sugar in urine were identified in
38.2%. Based on the ATP III criteria, metabolic syndrome was classified. 20.6% had 3
components, 28.4% had 4 components, majority i.e. 51% had 5 components identified.
In the present study, a statistically significant association was observed between
metabolic syndrome components and PPBS, Total cholesterol, Triglycerides, HDL, LDL
as the p-value calculated to be <0.05. In the present study, the mean serum ferritin
levels were 126.89 ± 51.77. There was a statistically significant association observed
between components of metabolic syndrome and serum ferritin levels as the p-value
calculated to be <0.05. In the present study, a significant relation was observed between
serum ferritin and waist circumference (r=0.33, pvalue<0.05), Total Cholesterol
(r=0.310 pvalue<0.0001), and LDL (r = 0.326; p value <0.0001).

A PROSPECTIVE STUDY OF SERM CALCIUM, MAGNESIUM, URIC ACID AND LIVER ENZYMES IN PREGNANCY INDUCED HYPERTENSION

Dr.Borra Dharmendhar, Dr.Laxmi Chapidi, Dr.Ketham Veera Sudhakar, Dr.Kankata Jhansi Rani

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 1328-1333

Introduction: Hypertensive disorders in pregnancy (HDP) are one of the deadly triads, along with hemorrhage and infection, and are responsible for 10.8% of maternal mortality in India. In preeclampsia and eclampsia, significant changes are seen in various biochemical parameters like uric acid and serum calcium. Hyperuricemia due to oxidative stress is associated with deleterious effects on endothelial dysfunction, oxidative metabolism, platelet adhesiveness, and aggregation. Hence, elevated serum uric acid is highly predictive of increased risk of adverse maternal
and fetal outcomes. Blood calcium has a relaxant effect on the blood vessels of pregnant women.
Materials and Methods: A prospective study was conducted at the department of Obstetrics and Gynecology, Kakatiya Medical College and MGM hospital, Warangal from1st October 2021 to 30th September 2022 (1 year).We have selected 100 cases and 100 controls. The control group was women who fulfill the same previously mentioned criteria, but who did not develop hypertension during the 3rd trimester. They were all normotensive with a systolic blood pressure of 130 mmHg or less and a diastolic blood pressure of 80 mm Hg or less.
Results: The present study includes 100 cases with pregnancy induced hypertension and 100 controls with normal healthy pregnancy. Age Distribution in Study Population Mean ± SD of age showed no significant difference with Mean ± SD of cases at 22.62 ± 3.61 yrs. compared to that of controls at 23 ± 4.04 yrs. and a p-value of 0.62. Gestational Age in Study Population Mean gestational age showed high significance with Mean ± SD of cases at 36.38 ± 4.19 weeks compared to that of controls at 39.62 ± 1.16 weeks with a p value of < 0.001.
Conclusion: Possibly, serial measurements of the serum uric acid and liver enzymes from early pregnancy can bring forward a selected group of high risk women for treatment. Thus, it can be concluded that Calcium and Magnesium can be evaluated at an early date so that such mineral deficiencies can be treated by appropriate Calcium and Magnesium supplements. Uric acid and Liver enzymes can possibly be used as biomarkers for identifying and avoiding adverse pregnancy outcomes by prompt intervention

Assessment of cardiovascular status of medical students during and after the examination

Dr.Richa Singh; Dr.Rajiva Kumar Singh

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 11, Pages 5833-5837

Background:Stress starts while the emotional, environmental, physical and social needs of
the individuals compete with one another, and exceed the ability of the individual. The
present study was conducted to assess cardiovascular status of medical students during and
after the examination.
Materials & Methods: 120 first year medical students were recruited. Parameters such as
height, weight, pulse rate, systolic blood pressure and diastolic blood pressure were
recorded before, during and after the examination as per WHO standards.
Results: Out of 120 subjects, males were 55 and females were 65. The mean SBP (mm Hg)
in males before, during and after examination was 110.2, 124.8 and 126.2 respectively. In
females, it was 106.4, 128.2 and 130.4 respectively. The mean BBP (mm Hg) in males
before, during and after examination was 74.2, 80.4 and 86.2 respectively. In females, it
was 72.8, 82.4 and 88.2 respectively.
Conclusion: Systolic blood pressure and diastolic blood pressure showed statistically
significant increase during examination and after examination