Online ISSN: 2515-8260

Keywords : antifungal

Chitosan – A naturally occurring viable alternative to Nystatin as an anti-fungal agent incorporated in heat polymerised denture base resin

Trunaya Bhatlekar; Siddharth Swarup; Swapnil Kurhade; Manish Shivaji Jadhav; Dhananjay Gandage; Amit Jagtap

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 11, Pages 5904-5915

Aims and Objectives: To evaluate and compare the antifungal efficacy of low molecular weight chitosan and nystatin by their inhibitory action on candida biofilm formation on Triplex heat cure denture base after 7 days and 14 days. Materials and Methods: A total of 10 specimens were fabricated using the Triplex heat cure PMMA acrylic resin by the conventional compression molding technique.Candida albicans biofilm was allowed to form over a period of 72 hours on all the specimens after pre-treatment with artificial saliva. Two groups of 5 specimens each were established. Group A was treated with low molecular weight chitosan suspension and group B was treated with nystatin suspension, both on the 4th day after biofilm formation. The treated specimens were now stored in a yeast nitrogen base broth medium to complete the time period of 7 days for initial maturation of the biofilm. The CFU count of candida colonies was recorded on the 7th day in both the groups.

Evaluation of Antibacterial Property of Medicinal Liquid Soap having JusticiaadhatodaL.(Adhatoda)Leaf Extracts

KulBhaskar .

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 3, Pages 882-891

Soaps are the products of basics aponificationreactions (Chukwulozie, 2014). Theyare in useamong society
from its discovery by the ancientBabylonians as acleansing material(Warra,2010).Currently,therearealarge
numberofcommercially available medicinal soapswhich come mainly as solid bar or liquid soaps. The
difference between solid and liquid soaps isthatinsolidsoapNaOH is used as base,whereas in liquid
soapsKOH is used as base in there preparation (Chukwulozie,2014).