Online ISSN: 2515-8260

Keywords : Acne vulgaris


Use of Botulinum Toxin in Treatment of Acne Vulgaris

Asmaa Osama Al Azazy, Amany Nassar,Khaled Gharib

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 4, Pages 1312-1319

Background:Acne vulgaris is a common inflammatory disorder involving the pilosebaceous unit. The
pathogenesis is multifactorial, involving four key factors with interrelated mechanisms: increased
sebum production, hyperkeratinization of the follicular infundibulum, inflammation, and
Cutibacterium acnes. Botulinum toxin (BoNT)is a potent neurotoxin protein derived from the
clostridium botulinum bacterium. It exerts its effect at the neuromuscular junction by inhibiting the
release of acetylcholine, which causes temporary chemical denervation. At the cellular level,
botulinum toxin functions by cleaving a synaptic protein (synaptosomal-associated protein of 25 kDA
[SNAP-25]) on the internal surface of neuronal membranes, thereby inhibiting vesicle fusion and
release of acetylcholine.

Comparative Study on Buffered 50% Glycolic Acid and 0.5% Salicylic Acid Solution Vs Jessener’s Solution in Egyptian Patients with Acne Vulgaris.

Rewan Hossam; Elsayed Khater; Mohamed Khater

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 2, Pages 2401-2411

Background: Acne vulgaris is a chronic inflammatory disorder of the pilosebaceous unit that is associated with significant psychosocial repercussions. Chemical peeling is a documented option in the treatment of active acne. Glycolic acid belongs to the group of α-hydroxy acids is used as a superficial or medium depth peel in acne treatment Jessner’s solution (JS) peel is formulated by Dr. Max Jessner to minimize complication from resorcinol, namely contact
dermatitis. Salicylic acid also decreases in inflammatory lesions

ASSESSMENT OF KNOWLEDGE REGARDING ACNE VULGARIS AMONG SECONDARY SCHOOL STUDENTS IN MAKKAH ALMUKARRAMAH, 2019

Fouad Saeed Masoud Al Sharif, Ahmed Emera Salem Alsobhi, Mohammed shaker, Hussain Abdullah Alsharif, Hattan Omar Ibraheem Almanjaf Hanaa Mohammed Shabain, Abdallah Abdulrahman Basheikh, Faisal khaled Albrkati, Mazen Mubarak Awad Baqazi, ArwaYahya H Zakri

European Journal of Molecular & Clinical Medicine, 2019, Volume 6, Issue 1, Pages 471-482

Background: Acne, also known as acne vulgaris, is a long-term skin disease that occurs when hair follicles are clogged with dead skin cells and oil from the skin. It is characterized by blackheads or whiteheads, pimples, oily skin, and possible scarring. It primarily a Acne vulgaris is one of the commonest skin disorders which dermatologists have to treat, mainly affect adolescents, though it may present at any age. Acne is definite as multifactorial chronic inflammatory disease of pilosebaceous skin diseases are common, especially in the developing countries. Mental health disorders are prevalent among those with skin diseases and affect their life and their treatment. Anxiety is one of the psychiatric disorders, and its symptoms were found among the patients with skin diseases. effects areas of the skin with a relatively high number of oil glands, including the face, upper part of the chest, and back. The resulting appearance can lead to anxiety, reduced self-esteem and, in extreme cases, depression or thoughts of suicide.Acne vulgaris is a common condition extremely prevalent among teenagers and young adults under the age of 24 years. Nearly 85% of adolescents in this age group experience some degree of acneAcne vulgaris is a skin disease of chronic inflammatory nature. Although acne is not a life threatening, it has a deleterious impact on patients' social and psychological health.
Aim of the study:to assessment of Knowledge regarding acne vulgaris among secondary school students in Makkah.
Method:A cross-sectional study design. The current study was conducted Male and female secondary school students from selected governmental schools in Makkah. The total the sample size calculation will be 200 students. Female and male.
Results:Conclusion:Patients with dermatological diseases have a high level of anxiety and worry, especially with acne and skin disease affecting visible areas like the face. Further studies are required in Saudi Arabia to explore the true estimates of this problem.