Online ISSN: 2515-8260

Keywords : Perceived stress scale


OXIDATIVE STRESS AND PSYCHOLOGICAL STRESS AMONG SUBJECTS WITH RECURRENT PREGNANCY LOSS

Ratheesh GB, Josekumar VS, Sumitha Prabhu PS, Parvathy S, Poornima R Varma, Gayathry A, Dinesh Roy D

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 7, Pages 539-547

Recurrent pregnancy loss (RPL), known popularly as recurrent miscarriage, is a clinical condition of two or more failed pregnancies, affecting 12-15% of total pregnancies. Besides genetic and anatomical abnormalities, stress and anxiety impart a vital role in repeated abortions. The Perceived Stress Scale, an extensively used psychological tool for assessing the perception of stress in an individual, was taken for evaluating the role of psychological stress among subjects with RPL. The oxidative stress marker, malondialdehyde (MDA) and several other clinical parameters were also analyzed among 150 women with RPL and 110 healthy women with one or two children. The study concluded that RPL individuals are shown to have higher rates of oxidative and psychological stress with elevated MDA concentration and PSS score respectively. 

EVIDENCE OF INCREASED PSYCHOLOGICAL STRESS AND SOMATIC DNA DAMAGE AMONG WOMEN WITH RECURRENT ABORTION

Ratheesh GB, Josekumar VS, Aswathy Sundaresh, Dinesh Roy D

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 4, Pages 1023-1030

Recurrent abortion refers to the loss of two or more pregnancies before 20 weeks of
gestation. Recurrent abortion could be because of environmental, physiological,
endocrinological or biochemical factors. Perceived stress scale (PSS) is the most widely used
psychological tool to scale the perception of stress and is a measure of the degree to which
situations in one’s life are appraised as stressful. However, the role of psychological stress in
recurrent abortions has not been examined properly. Hence, the present study was conducted
to evaluate the perceived stress in women with recurrent abortions with no known risk factors
for obstetric complications and to determine demographic and pregnancy-related factors
associated with stress. In the current study 136 women with recurrent abortions were included
in the test group and 110 healthy women with one or two children were selected as control
subjects. Perceived stress scale (PSS) was employed to assess the women’s stress status and
correlate it with various demographic, physiological and clinical characteristics of the study
subjects.Cytokinesis-block micronuclei (CBMN) assay was also performed to quantify the
extent of somatic DNA damages among subjects with recurrent abortions. Women with
recurrent abortion showed a statistically significant increased score of PSS and CBMN
frequency than the control subjects.

ASSESSMENT of IMPACT of COVID-19 (NOVEL CORONA VIRUS DISEASE) on ADULT INDIAN POPULATION: A CROSS SECTIONAL QUESTIONNAIRE BASED SURVEY

Shweta Patel; Manindra Rajak; Kamini Khatak; Ranjana Patnaik; Diwakar Chauhan

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 9, Pages 10-23

Background As the pandemic COVID-19 (due to novel Corona virus) is widely spreading across the globe, it is creating extensive fear, anxiety, apprehension and stress. These are all inevitable and growing reactions to the changing and uncertain situation in which all of us find ourselves. Objectives This study was carried out to assess the psychological impact of the novel, unprecedented situation arising due to pandemic in adult Indian population. Method The data was collected with self-reported questionnaire based survey. The survey was circulated in social media as Google form and participation was completely voluntary. Data was statistically analysed by using chi square test for the calculation of significance. Results The responders had moderate level of perceived stress and anxiety 71%; 63.1% were found to be above average in terms of wellness, 80% were reported to smoke/chew tobacco/consume alcohol and 98.1% were well aware of COVID-19 and seriously followed social distancing. Conclusion Since disruptive effect of COVID-19 social distancing is dominating our daily lives, it is important to maintain connection. Anxiety and fears of each and every individual should be acknowledged and better understood by other individuals, communities and caregivers.