Online ISSN: 2515-8260

Keywords : deficiency

Impact and Influence of Deficiency of Vitamin D on Asthma in School-Aged Children

Zainab S Abdul_hafed Shagloof ,Najia Albashir Mahdawi .

European Journal of Molecular & Clinical Medicine, 2023, Volume 10, Issue 2, Pages 787-798

Over the past few decades, environmental modifications (lower availability to sunlight owing to operating indoors or use of protective clothing and sunblock; food modifications) have been mainly blamed for vitamin D and inadequacy in the wider public. Being overweight, living in the inner-city and having African American ancestry are possible causes for asthma and vitamin D insufficiency. While the musculoskeletal effects of chronic insufficiency of vitamin D are very well recognized, a variety of other illnesses, particularly respiratory problems, have recently been related to vitamin D insufficiency. The potential significance of vitamin D as an increasing mediator that supports lung health is becoming well understood. In children with asthma, vitamin D insufficiency appears to be more common. According to epidemiological data, children with asthma with low blood levels of vitamin D suffer from more pain, exacerbations, lung damage, medication usage, and severe illness. Research published in vitro has shown that adult asthmatics' steroid sensitivity is improved by vitamin D. By preventing disease, in particular by retaining regulatory T cells, and by directly inducing intrinsic antimicrobial systems, vitamin D may have a significant impact on lung health. To resolve the diagnosis and treatment significance vitamin D could have in treating asthma in the long term, more investigations are essential to completely comprehend the impacts of vitamin D in preserving airway homeostasis. Along with prospective defence mechanisms like antiviral impacts and augmented steroid attentiveness, considerable uncertainty concerning the impacts of vitamin D insufficiency and inadequacies in kids with asthma and a thorough analysis of present experimental and observational studies substantiation of relationship among vitamin D levels and asthma or bronchitis comorbidities.


Dr Shivu Bidari , Dr Sankar Kalairajan , Dr Praveen Gandhi,Dr Manju M

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 7, Pages 7194-7207

Background: Cardiovascular disease (CVD’s) are the chief cause of mortality in country like India, were quarter of all mortality are due to CVD. Vitamin D inhibits inflammation through a variety of mechanisms. The aim of the study was to assess the influence of vitamin D level on the  lipid profile of patients of coronary artery disease.
Material & Method: The present hospital based observational study was conducted among the patients who are more than 18 yrs with signs, symptoms and investigation (ECG) of coronary artery disease admitted to the AVMC hospital. Patients with chronic kidney disease, patients with elevated CRP, fever, patients with cancer and on supplementation of Vitamin D3 were excluded from the study.  The lipid parameters and vitamin D3 were measured to assess the relation.
Results: In present study total of 160 patients included with mean age of patients was found to be 51.75±8.58yrs, 68.8% were male. Vitamin D deficiency was seen in 50%, insufficiency in 40.6% and sufficiency in 9.4% patients. We found a significant higher incidence of dyslipidemia among the patients with deficiency and insufficient vitamin D compared to sufficient vitamin D levels.(p<0.05) Also there is significant negative correlation of total cholesterol and LDL cholesterol with the vitamin D3 level and a significant positive correlation with the HDL cholesterol. (p<0.05)
Conclusion: There is higher incidence of presence of vitamin D deficiency and insufficiency among the patients with coronary artery disease in the present study

Comparative analysis of serum vitamin d level in under five aged children with acute lower respiratory tract infection

Dr. C D Aundhakar, Dr. Riyaben Chauhan .

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 7, Pages 8887-8890

Background: To analyse serum vitamin D level in children under 5 years of age with acute lower respiratory tract infection.      
Materials & methods:A total of 50 children were enrolled. The age of subjects was under 5 years either as inpatients or outpatients with acute lower respiratory tract infections. 40 subjects were present with acute lower respiratory tract infection.  Venous blood specimens were collected from cases and controls to study serum 25-hydroxyvitamin D.
Results: Vitamin D levels divided into sufficient, insufficient and deficient. The case group included 40 subjects and 30% had insufficient vitamin D levels and 70% had deficiency of vitamin D. In the control group, 60% had sufficient vitamin D and 10% had deficiency.
Conclusion: Vitamin D deficiency among children should be measured with acute lower respiratory infections compared to controls.

Assessment Knowledge regarding Vitamin D deficiency among female adult attending the Primary Health clinic atMakkah, Saudi Arabia, 2021

Saud AbdulhaiGari, Wesaam Mohammad Jamal Ghafuri, Abeer Mohammed Noor Hosawi, Mohammed Abed Gurunfula

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 4, Pages 3123-3137

Vitamin D deficiency is prevailing in Saudi Arabia. Recent national data indicated an inverse association between vitamin D status and coronary heart disease (CHD), which increases concerns about vitamin D deficiency as a serious public health problem. Therefore, the current study aimed to Assessment Knowledge regarding Vitamin D deficiency among female adult attending the Primary Health clinic at Makkah, Saudi Arabia, 2021. Saudi Arabia has one of the highest reported incidence of vitamin D deficiency in studies conducted worldwide. However, there has been very limited exploration of vitamin D related knowledge, attitudes and practices among female adult in Saudi Arabia. However, the case of vitamin deficiency is reported to increase in many female Saudi Arabia worldwide, especially in Saudi Arabia. Mothers, having adequate knowledge about vitamin D and its supplementation, may lead to possible lowering of the cases of vitamin D deficiency and its complications


Hala Mohamed Sanad; Gayathri Priya; Jameela Jassim Mukhaimer; Govindaraj V. Asokan; Safia Belal

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 9, Pages 180-191

Background: Vitamin D deficiency is a common health problem in many countries, including Bahrain. However, little data exists about the awareness and the level of knowledge of vitamin D among Arab Gulf populations. Method: A cross-sectional study design was employed. A self-administered questionnaire was administered to an adult sample of 335 participants seeking information on their knowledge about vitamin D. Findings: 81.2% of the study participants had unsatisfactory total knowledge score of vitamin D. Level of education and the sources of information about vitamin D were the main significant factors that appear to influence the participants’ vitamin D awareness status. Most the participants recognized that exposure to sunlight encourages the production of vitamin D, however, only a small proportion of participants were aware of the sources of vitamin D in daily food intake and health consequences of vitamin D deficiency. Conclusion: There is inadequate knowledge and awareness regarding vitamin D deficiency among adult Bahrain population. Health campaigns are urgently needed in order to improve the community’s knowledge about the benefits and sources of vitamin D

Grape Shinny For Prevention And Nutritional Support Of Micronutrient Deficiency In Mothers And Children

Saydullo Rasulov; Gulchehra Akhmedova; Khabiba Rustamova; Shokir Turamkulov; Nodira Nurullayeva

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 7, Pages 4908-4916

Development of new methods for early diagnosis, nutritional support using national food products with a high content of pharmacological nutrients (grape shinny) in the prevention of deficiency, macro- and microelements in the "Mother-child" system.To prevent and correct micronutrient deficiency, the content of macro - and microelements in food products rarely used by the local population - grape shinny (molasses), was determined in the laboratory of activation analysis of the Institute of Nuclear Physics of the Academy of Sciences of the Republic of Uzbekistan by neutron activation method. The study of the sugar content in the composition of grape shinni was conducted in the laboratory of the Khovrenko winery in Samarkand.In mothers and their infants, the high-risk group for micronutrient imbalance was the highest, The composition of grape shinny revealed a high concentration of calcium, potassium, zinc, iron, copper and in trace concentrations of abiogenic, toxic elements, which confirms the safety for humans.


Dr. Kalai Selvi A; Dr. Saravanan; Dr. M.S. Kannan

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 4, Pages 1653-1657

Expansion has been one of the oldest means and also conservative method of gaining space and correcting the intermaxillary and dental arch relationships primarily in transverse direction. As clinicians we all rely on some form of rapid or slow palatal expansion appliances to produce maxillary change. Various appliances and treatment techniques have been developed and used to correct the transverse discrepancies. The most common is rapid maxillary expansion (RME) performed with a tooth-anchored expander. However the predictability of orthopedic expansion is greatly reduced after 15 years of age. Due to this reason, it has been proposed that the MARPE is an effective alternative to maximize the skeletal effects in adults and also to avoid invasive surgical procedures like SARPE .


Sammar Ali M Jalal, Mohammed Ahmed Omar Almahmudi, Amal abdulkader habhab, Mohammad Hassan Saqeer Alhothali, Nader Mohammad Alharbi, Ahlam Saleem Almagnoni Wajdi Bashah Khider Alnadwi, Nada Mohammed Saaed Alharbi, Rami Husein Saad Almasri

European Journal of Molecular & Clinical Medicine, 2019, Volume 6, Issue 1, Pages 139-149

      Vitamin D is one of the major vitamin and very essential for maintenance of normal growth and development of strong bones. It is often referred to as the "sunshine vitamin" because it can be synthesized in the body from the ultraviolet rays provided by the sun. Vitamin D is known to have essential roles in the human body. However, the case of vitamin deficiency is reported to increase in many adult worldwide, especially in Saudi Arabia. Vitamin D deficiency is associated with numerous chronic diseases including cancer, heart disease and diabetes type 1 and 2. It is currently estimated that one billion people suffer from vitamin D deficiency worldwide. Sunlight is the main and natural source of vitamin D and most foods contain very little amount of it. The main action of vitamin D is to help calcium and phosphorus in our diet to be absorbed from the gut.
 Aim of the study: The study’s aim was to assess the knowledge regarding vitamin D deficiency ​among female adult attending the primary health clinic at Makkah at Saudi Arabia
Methodology: Across sectional descriptive study was conducted among female adult attending to clinic in PHC at Makkah, Saudi Arabia city, during the October to December, 2019. Our total participants were (150).  Results: Major findings of the study were (38%) adult women were in the group of age between 25 to 35 years. The majority of the women (84.67%) “married” status. The majority of the women were (49.33) secondary level of education, regarding chronic disease, most of the mothers in the study were found to have no chronic disease were (62.00%). The income level of (56.0%) of the respondents ranged average, the majority of the women were (42.0%) Sources of knowledge doctor.
 Conclusion: Vitamin D deficiency is prevalent among the various age groups in our country due to various factors. So, Awareness programmes have to be conducted to make the general public including the females aware of the vitamin D, its deficiency, causative factors and the preventive measures. So this study was done this study was conducted assessment the knowledge towards vitamin D deficiency, sun exposure, supplementation in a sample of adult female attending the primary health clinic at Makkah, Saudi Arabia Saudi Arabian.