Online ISSN: 2515-8260

Keywords : Prostate cancer (PCa) is the most common cancer among men and the second leading cause of


Comparison of B lymphocyte effects of laparoscopic versus open prostatectomy in prostate cancer patients.

Paulius Bosas; Gintaras Zaleskis; Bret Andrew Hudson; Feliksas Jankevicius; Vita Pasukoniene

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 3, Pages 437-441

The preoperative B-cell counts (CD 19+) appeared to be more reduced by laparoscopic prostatectomy when compared with open surgery. These findings are important because accumulating evidence suggest that the B-cell subsets emerged in response to prostate cancer exhibit association with unfavorable prognosis. High per cent of B- cells infiltrating tumor were shown to be associated with more aggressive disease. The B-cell depleting therapies used with different prostatectomy settings should be closely monitored to make timely adjustments to peripheral CD19+ counts