Online ISSN: 2515-8260

Keywords : malondialdehyde


OXIDATIVE STRESS AND PSYCHOLOGICAL STRESS AMONG SUBJECTS WITH RECURRENT PREGNANCY LOSS

Ratheesh GB, Josekumar VS, Sumitha Prabhu PS, Parvathy S, Poornima R Varma, Gayathry A, Dinesh Roy D

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 7, Pages 539-547

Recurrent pregnancy loss (RPL), known popularly as recurrent miscarriage, is a clinical condition of two or more failed pregnancies, affecting 12-15% of total pregnancies. Besides genetic and anatomical abnormalities, stress and anxiety impart a vital role in repeated abortions. The Perceived Stress Scale, an extensively used psychological tool for assessing the perception of stress in an individual, was taken for evaluating the role of psychological stress among subjects with RPL. The oxidative stress marker, malondialdehyde (MDA) and several other clinical parameters were also analyzed among 150 women with RPL and 110 healthy women with one or two children. The study concluded that RPL individuals are shown to have higher rates of oxidative and psychological stress with elevated MDA concentration and PSS score respectively. 

THE STATE OF FREE-RADICAL OXIDATION OF LIPIDS IN EXPERIMENTAL MYOCARDIAL INFARCTION IN RATS

Baykulov Azim; Djalilov Mustafo; Eshimov Dusmurat; Yusupova Saodat; Kim Oksana; Sovetov Kаrоkul

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 3, Pages 816-820

Lipid peroxidation products are capable of inhibiting the activity of enzymes of glycolysis and oxidative phosphorylation, inhibiting the synthesis of protein and nucleic acids, inhibiting many membrane-bound enzymes and thus exerting a pronounced damaging effect on cells and the body as a whole. It is of particular interest to study the intensity of lipid peroxidation in the body during myocardial infarction, which was the price of this study.