European Journal of Molecular & Clinical Medicine

Present research intends to evaluate the impact of post-acne scars on quality of life.
Methods: The Prospective correlation cross-sectional study was effected out after enrolling 100 cases of post-acne scars aged 16 years or more in an institution based tertiary health care center. The quality of life of the patients was evaluated using the Dermatological Life Quality Index (DLQI) questionnaire and the acne scar severity was evaluated using the Goodman and Baron Quantitative grading scale. Institutional Ethics Committee clearance was obtained before the start of the study.
Results: The result showed that maximum patients, 62 %, were in the second decade, followed by 21 % patients who were in the 31 – 40 years age group. The gender-wise distribution showed that females contributed majority of the cases (51 %) and males contributed 49 % of the total cases.  Only 30% of the patients had prior family history of post-acne scars. The mean age of onset of acne was 18.11 years whereas that of onset for post-acne scar was 21.43 years. The maximum DLQI score was 14 and mean DLQI score for acne scarring was 5.31. We found that, higher the grade of scarring more was the mean DLQI score. We found a positive correlation between DLQI and the post-acne scar severity total score and this was statistically significant.
Conclusion: Acne and acne scarring are influenced by non-dermatological aspects like perceptions, personality, age, social and cultural circumstances as well as disease characteristics such as onset, duration and severity. Assessing QOL first at baseline offers valuable insight into patient’s perspectives. Our research demonstrated that post-acne scars significantly diminish the quality of life in young adults. The study’s findings also suggest that the quality of life worsens with increased severity of scarring. Therefore, individuals with acne should be treated promptly and effectively, to avoid acne scarring or to reduce its severity.

Background:Lipid profile in patients with cerebrovascular disease and to determine
significant correlation between them. To ascertain the effect of age and sex on serum lipid
profile.The diagnosis of diabetes in a stroke patient would change the initial management of
that patient, specifically with respect to other risk factors like lipid and blood pressure
management.
Aims and Objectives: To study lipid profile in diabetic and non-diabetic newly diagnosed
young stroke patients.
Materials and Methods: A total of 138 patients were admitted during study period were
selected by simple random sampling with acute stroke in the study. Fasting total cholesterol,
triglycerides, high density lipoprotein cholesterol (HDL-C) and low density lipoprotein
cholesterol (LDL-C) were measured from venous blood samples.
Results and Observations: The mean HbA1c for group D and group ND were 9.04±1.02
and 4.85±0.45 respectively. This difference in HbA1c among patients in two groups was
statistically significant. The mean values of LDL, VLDL, total cholesterol and triglycerides
showed significant association between two groups. Levels of HDL were significantly lower
in Group D as compared to Group ND.
Conclusion: The lipid profile of LDL, VLDL, total cholesterol and triglycerides showed
significant higher range in diabetic patients as compared to non-diabetics while HDL was
lower in diabetic patients as compared to non-diabetics.

Introduction: Squamous cell carcinoma (SCC)s specifically of the tongue usually is seen in the senile population with a long standing tobacco habit. But recently the trend has changed to incidence of TSCC in younger adults with no risk factors. Hence we aim to conduct a systemic review and metanalyse to assess the prevalence and risk factors of tongue carcinoma in the younger group of patients. Materials and methods: We conducted the search for the data from the online sources like the “EMBASE”, “Pubmed”, “Scopus” and other sources. Only human studies were collected. Terms searched were CBCT, microtomography, permanent teeth, and root canal morphology. The data extraction and meta-analysis were based on the PRISMA guidelines. Out of the 109 articles, only 23 were selected based on the inclusion and exclusion criteria. For the assessment of the risk factors and the variables the statistical analysi s was done keeping p<0.05 as significant. Results: we observed that most of the subjects were at ages 30-50 years. The majority of reports were <40 years of age. Almost equal gender distribution was seen. No association between the habits was seen in the younger adults.