Online ISSN: 2515-8260

Keywords : red blood cells


New Aspects in the Study of Clinical and Morphological New Aspects in the Study of Blood in Type II Diabetes Mellitus

Tatyana V. Pavlova; Vladimir F. Kulikovskij; Anton N. Kaplin; Irina I. Povalyaeva; Lyudmila O. Zemlianskaia; Lyubov A. Pavlova

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 128-133

The aim of the research was to study red blood cells in type II diabetes mellitus (DM),
both an independently occurring disease, and in combination with hypertension, using
innovative research methods (atomic force and scanning electron microscopy with
elemental analysis). In the course of the study, we observed 20 patients aged 40 to 50
years. All of them were divided into groups of 5 people: without somatic and endocrine
pathology and infectious diseases; with moderate type II DM; stage II hypertension;
with a combination of type II DM and hypertension. Each has passed the necessary set
of generally accepted clinical and laboratory examination methods together with related
specialists (therapist, endocrinologist, neurologist, ophthalmologist). Blood was taken
from each patient for subsequent light, atomic force and scanning electron microscopy.
A morphometric analysis of the tissues in the Ntegra-Aura instrument was also
performed. We observed the most pronounced changes in the structure of erythrocytes
in people with a combination of type II DM and hypertension: the number of
degenerative forms increases sharply, and the number of discocytes decreases. In this
regard, such altered red blood cells can’t perform their functions in full. The article
substantiates the possibility and future prospects of using atomic force and scanning
electron microscopy with elemental analysis for independent type II DM, and in
combination with arterial hypertension.

FEATURES OF HEMOGRAM INDICATORS FOR CIRROSIS OF THE LIVER

I.I. Bakhriev .; SH.Yu., Beknazarov; S.J. Khojanazarova; E.A. Eshbayev

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 2473-2482

Abstract: It is known that, against the background of the progression of chronic hepatitis,
significant changes in blood elements are occurring. The number of red blood cells, the
level of hemoglobin, the color index, the content of reticulocytes, platelets and leukocytes
in patients with chronic diffuse diseases of the liver are significantly lower than in people
without diseases of the hepatobiliary system, and blood counts decrease as the activity of
inflammation in the liver and the transformation of chronic hepatitis B increase cirrhosis
of the liver. The purpose of this work is to identify the features of the hemogram in patients
with cirrhosis of the liver.