European Journal of Molecular & Clinical Medicine

Introduction: While there are considerable enthusiasm and anticipation for the COVID-19
vaccine, little is known about vaccine hesitancy specifically for COVID-19 in the general
population. Identifying specific populations, their characteristics with regards to vaccine
knowledge, awareness & acceptance will help as key components of a successful vaccination
strategy. Hence the present study was carried out to assess the knowledge, awareness &
acceptance of COVID-19 vaccination among general population of urban Raigarh,
Chhattisgarh.
Methods: A community-based cross-sectional study was conducted among 400 participants
of urban Raigarh regarding knowledge, awareness & acceptance of COVID-19 vaccine from
April-June 2021. The methodology comprises of primary data collection through survey in a
pre-designed pre-tested proforma by face to face interview.
Results: Total 400 participants among general population who had an average age of 34.3
years ±11.8 years with slight male preponderance (53.2%). Nearly half (58.2%) of
participants were from the slum, (45.2%) came under middle socio-economic class and (49%)
were self-employed. Majority (77.25%) knew about COVID-19 vaccination programme,
while (46.75%) knew about common side effects of vaccine. More than half (54.25%) were
aware that it boost up immunity against COVID-19 infection and (77.5%) were having good
knowledge regarding COVID-19 vaccination, and (36.5%) were afraid of taking COVID-19
vaccine, while (39%) were concerned about its side effects.
Conclusion: The study identified that majority of responders were aware regarding COVID-
19 vaccine, still many have doubts & concerns about its potential efficacy and safety thereby
providing an important outlook for feasible interventional awareness programs to enhance
vaccination rates. The study also identified that the concerns regarding the vaccine adverse
effects acted as the leading barrier for vaccine acceptance.

As a major virus outbreak in the 21st century, the Coronavirus disease 2019 (COVID-19) pandemic has led to unprecedented hazards to mental health globally. While psychological support is being provided to patients and healthcare workers, the general public's mental health requires significant attention as well. This systematic review aims to synthesize extant literature that reports on the effects of COVID-19 on psychological outcomes of the general population and its associated risk factors. A systematic search was conducted on PubMed, Embase, Medline, Web of Science, and Scopus from inception  following the PRISMA guidelines. Relatively high rates of symptoms of anxiety , depression , post-traumatic stress disorder , psychological distress , and stress  are reported in the general population during the COVID-19 pandemic . Risk factors associated with distress measures include female gender, younger age group , presence of chronic/psychiatric illnesses, unemployment, student status, and frequent exposure to social media/news concerning COVID-19.The COVID-19 pandemic is associated with highly significant levels of psychological distress that, in many cases, would meet the threshold for clinical relevance. Mitigating the hazardous effects of COVID-19 on mental health is an international public health priority.