Online ISSN: 2515-8260

Keywords : substances of low and medium molecular weight (LMMWSs)


Clinical and Biochemical Parameters of Patients with Oral Galvanosis

Aleksandr V. Tsimbalistov; Ekaterina S. Mikhailova; Irina V. Voytiatskaya; Irina. P. Ryzhova; Aleksandr A. Ponomarev

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 134-140

The clinical and biochemical parameters of patients with oral galvanosiswere studied. A
comprehensive examination of patients with galvanosis, which included an assessment
of dental and somatic status, as well as a study of the content of low- and mediummolecular-
weight substances (LMMWSs) in plasma, erythrocytes and mixed saliva was
held.Patients with galvanosis who were also likely to have diseases of the digestive
system, diseases of the circulatory system, diseases of the nervous system prevail
among comorbidities. Consequently, the course of the underlying disease in the
examined patients is complicated by concomitant somatic pathology due to the observed
polymorbidity.The absolute values of the current value recorded in the oral cavity do not
correlate with the subjective and objective manifestations ofgalvanosis. A positive
average correlation was found between the severity of the development of galvanosis
and the level of impedance in the oral cavity(r=0.573, p<0.001).The high level of
LMMWSs in the blood (22.12±0.77c.u.) and mixed saliva (29.88±0.62c.u.) in patients with
galvanosis indicates endogenous intoxication resulting from the impairment of many
organs and systems, which is confirmed by the history and examination data. The
placement of dental material into the oral cavity increases the degree of toxic load and
has a negative impact on the surrounding tissues and the body as a whole.