Online ISSN: 2515-8260

Keywords : mushroom

Antimicrobial effect of mushroom and ozone gas individually or combined

Shaimaa Ahmed Alrafee, Maha Ahmed Niazy, Khaled Hussein Metwaly .

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 3083-3089

Purpose: The purpose of this in-vitro study was to evaluate the effect of mushroom extract and ozone gas on streptococcus mutans.
Materials and methods: Suspensions of streptococcusmutans (NCTC 10449) in salt buffer were used to check the antimicrobial activity of aqueous extracts of mushroom and ozone. The test samples were divided as follow:Group I: Aqueous extract of mushroom, Group II: ozone gas, Group III: Aqueous extract of mushroom+ ozone gas. After exposure to different treatment, aliquots of the samples were spread on agar plate which was incubated at 37 C for 2 days. The number of bacterial colonies (CFU) on the plates was counted.
Results: There was a significantdifference between different groups (f=31.69, p<0.001). The highest value of bacterial count was recordedfor ozone therapy (8.97±0.18), followed by mushroom extract (8.69±0.45), while the lowest value of bacterial count was recorded for mushroom extract + ozone therapy (3.36±0.12).
Conclusions: mushroom extract + ozone gas show synergistic effect on streptococcus mutans.

Assessment of antidiabetic activity of hydroalcoholic extract of Volvariella volvacea

Pushpa P. Gupta; Shashikant Chandrakar; Amit Roy; Seema Verma; Neeta Gupta; Ram Kumar Sahu

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 3, Pages 1499-1509

Mushrooms (a macrofungus) have high dietary values and are used in cooking for ages. Some of them are also reported to have medicinal properties. Volvariella volvacea (V. Volacea) is an edible mushroom cultivated in East and South East Asia. This provides good nutrition is extremely suitable in human diet. The present work was planned to determine the antidiabetic potential of V. volvacea by exploring the glucose tolerance test and other vital serum profiles in normal as well as STZ-induced diabetic rats. The mushroom was subjected to hydroalcoholic extraction; the extract was divided into two equal portions. One part was dried by lyophilisation (LE) and second part was dried in hot air oven (ODE). The LE and ODE of V. volvacea was studied for antidiabetic activity. The extracts, in a dose dependent manner could significantly decrease the serum glucose level of diabetic rats. The results show that LE of V. volvacea exhibited more antidiabetic activity than ODE. The above result advocate that more study is required to proceed for developing a formulation of this mushroom to utilise its nutraceutical and medicinal properties