Online ISSN: 2515-8260

Keywords : Blood Glucose

Serum Electrolytes Levels in Patients with Diabetes Mellitus: An Experience from a Tertiary Care Hospital of Northern India

Amit Kumar Sharma, Dr. Sheikh Yasir Islam, P S Nayyer

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 1, Pages 1266-1273

Background: Blood glucose and electrolytes have a complicated relationship that is
influenced by a number of other factors such as age and concomitant conditions. As
there is paucity of such studies in India, so present study was to determine the most
prevalent electrolyte disturbances among diabetic in-patients and to explore an
association between blood sugar and electrolyte imbalances.
Materials and Methods: The present cross-sectional study was carried for a duration of
two years among 271 adult patients with diabetes mellitus admitted to the wards and
ICU in a tertiary care centre. Patient-specific information was collected in a structured
schedule and blood sample was collected for laboratory investigations after obtaining
written informed consent. All tests were performed at a 5% level of significance; thus,
an association was significant if the p value was less than 0.05.
Results: In present study (Table 1), the mean age of study subjects was 58.92 ± 13.15
years, with nearly equal representation from males (49.4%) and females (50.6%). The
mean duration of diabetes among subjects was 9.72 ± 6.57 years. The mean HbA1C was
7.65 ± 1.23 % which reflect uncontrolled diabetes. The most common electrolyte
imbalance among enrolled subjects was hyponatremia (33.6%). The mean levels of
serum sodium (group A: 132.82 ± 3.99 vs group B: 135.62 ± 5.12), were statistically
different (p<0.05).
Conclusion: The importance of evaluating serum electrolytes in patients with type 2
diabetes was presented in the study. Electrolytes, particularly sodium, chloride, and
potassium, become significantly disturbed as fasting blood glucose rises.

Effect Of Feeding At Different Levels Of Wheat Bran And Date Seeds Powder On Diabetic Rats

Dheyaa Salah Hussein

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 3, Pages 406-417

There is a global rise in the incidence of diseases like diabetes mellitus, atherosclerosis and cardiovascular diseases. Therefore, this study was designed to examine the effect of adding fine bran and date seeds powder as a sources of dietary fibers and active healthy components to prepare functional bread for lowering blood glucose and cholesterol levels. Sensory evaluation revealed that successful replacement of bread samples with 5,10 and 15% fine bran (Fb), 5 and 10% date seeds powder (Dsp) and the mixture of 5% fine bran + 5% date seeds powder. Bread supplemented with 10 and 15% fine bran contained 13.478% and 13.777% (g/100g) protein content respectively, while bread supplemented with mixture of 5% fine bran + 5% date seeds powder, and 10% date seeds powder contained 5.51 and 4.95 (g / 100g) of total dietary fibers respectively. The biological evaluation showed that rats fed on bread sample and its mixtures containing 15% fine bran , 5% date seeds powder, 10% date seeds powder and the mixture of 5% fine bran + 5% date seeds powder for 30 days significantly (p<0.05) reduced serum total cholesterol (TC), triglycerides (TG), low density lipoproteins (LDL), very low density lipoproteins (vLDL), while high density lipoproteins (HDL) increased. Also, data showed that rats fed on pan bread made from wheat flour substituted with different levels of fine bran and/or date seeds powder significantly lowered their blood glucose level.