Online ISSN: 2515-8260

Keywords : Minoxidil

Alopecia Areata Updated Management: Minoxidil Solution 5% and Microneedling with Anthralin Cream 1%.

HendDarwishGamil,Heba Mohamed Abdelatif,Mohammed HamedKhater

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 3, Pages 3738-3749

Alopecia Areata (AA) is an autoimmune disease of the hair follicle that presents as
non-scarring alopecia both in the scalp and non-scalp areas. The etiology of this disease remains
unknown ;however, a current hypothesis implicates T-cell-mediated autoimmunity that affects hair
follicles, as well as the up- regulation of inflammatory cytokines ,in the pathogenesis of disease
.The severity ranges from focal (patch-type AA) to total scalp hair loss (alopecia totalis) to entire
body hair loss (alopecia universalis).Microneedling (MN), also known as collagen induction
therapy, is a process involving repetitive puncturing of the skin with sterilized microneedles. Its
original conception can be traced back to 2012, when Orentreich and Orentreich developed the
concept of “subcision” or using hypodermic needles to induce wound healing in depressed
cutaneous scars. Anthralin is used in alopecia areata at concentrations ranging from 0.5 to 1 % for
20-30 minutes after which the scalp should be washed with shampoos in order to avoid excessive
irritation.Minoxidil stimulates hair growth only in cases of mild AA, but slight to no effects were
observed in patients with extensive AA. Only mild side effects of minoxidil were reported with no
evidence of systemic effects

Management of Telogen Effluvium: An Overview

Fathia Khattab MD, Areeg Rady MSC, Shrook Khashaba MD

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 3, Pages 3951-3958

Telogen effluvium (TE) is a diffuse, non-scarring hair loss
characterized by shortening of the anagen phase and precipitation of the telogen
phase that leads to consequent decreasing of the total hair volume. Identifying and
correcting the underlying cause is the most important component in management.
Minoxidil is mainly used for the treatment of male and female androgenetic
alopecia but it has a place in TE management. The goal of mesotherapy in
management of some types of hair disorder is to restore and increase local
microcirculation, provide nutritional input, slow down the programmed process of
follicular involution.