Online ISSN: 2515-8260

Keywords : Renal cyst


Adult Renal Cystic Disease: A Comprehensive Literature Review

Islam Ali Elsayed, Aya Salah AboArab, Ayman Fathy Zeid, Salem Ali Eldeeb

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 3, Pages 3778-3783

Renal cystic disease occurs as a result of cysts of varying sized localized in an enlarged kidney.
It can be classified into different forms such as autosomal-dominant polycystic kidney disease,
autosomal-recessivepolycystic kidney disease, unilateral renal cystic disease, renal simple cysts,
multicystic dysplastic kidney,pluricystic kidney of the multiple malformation syndromes and
medullary cystic disease. Recent studies showed that there is a relation between inherited cystic
disease and changes in a group of genes involved in the formation and function of bothprimary
cilia of the embryonic node and cilia in epithelial renaltubes. On the other hand, cysts in
acquired conditions occur as a result ofobstructive, stromal–epithelial malinductiveand
neoplastic mechanisms. Moreover, several genetic and acquired renal cystic diseases were found
to be linked to the development of renal cellcarcinoma. There are different approaches to
diagnose various types of renal cysts, while ultrasound and slice imaging are the main tools for
the diagnosis of simple renal cysts, Bosniak classification was selected as the basic method for
the diagnosis of renal cystic masses larger than 1 cm. In the current review we will discuss the
various types of renal cystic diseases and the main diagnostic approaches