Online ISSN: 2515-8260

Keywords : Traumatic Brain Injury


ASSESSMENT OF QUALITY OF LIFE AMONG PATIENTS UNDERGOING DECOMPRESSIVE CRANIECTOMY IN A TERTIARY CARE HOSPITAL OF EASTERN INDIA

Dr. Shivam Gour, Dr Partha Ranjan Biswas, Dr. Shubhamitra Chaudhuri, Dr Subhasis Ghosh

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 4, Pages 733-740

Introduction: Traumatic Brain injury is defined as an acute injury to the head caused by blunt or penetrating trauma or from acceleration/deceleration forces excluding degenerative, congenital problems. Decompressive craniectomy is being used as an effective measure in the management of TBI with prognosis being measured in terms of Glassgow outcome scale. However, the quality of life of such patients is often not assessed. Quality of life is a long term outcome phenomenon which must be effectively evaluated.
Objectives: To assess the quality of life of the patients undergoing decompressive craniectomy using EQ5D scoring scale.
Materials and Methods: This was an observational study conducted for 1.5 years in a Trauma care centre of Eastern India. The study included 100 study subjects. Informed consent was obtained from every participant and approval to conduct the study was obtained from Institutional ethics Committee.All post trauma patients who survived after decompressive craniectomy were followed up at 6 months post discharge to assess their quality of life using a pre-designed and pre-tested proforma containing information on the clinical profile. Quality of life was analyzed using the EQ5D scoring system at six months of discharge.
Results: The mean  SD age of the study subject was calculated to be 51.5  23.3 years. The commonest mode of injury was road traffic accident seen in 62% study participants. Almost 3/4th of the study subjects underwent surgery for non-diffuse traumatic brain injury within the first 24 hours of hospital admission. Among the 72 study participants that survived, EQ5D Index score to assess the quality of life was found good/ favorable in 86.1% patients and only 13.9% subjects had a poor/ unfavorable EQ5D Index score.
Conclusion: Majority of survivors after decompressive craniectomy showed a good functional outcome as analyzed by EQ5D. Improving patient selection and optimizing timing of the procedure may lead to favorable long term functional outcome in these very severely brain injured patients.

THE EFFECT OF HYPERTONIC SALINE SOLUTION (7%) ON INTRACRANIAL PRESSURE AND CEREBRAL PERFUSION PRESSURE IN PATIENTS WITH ISOLATED TRAUMATIC BRAIN INJURY

Murotov Temur Malik Nizomovich; Avakov Vyacheslav Ervandovich; Boymurodov Hasan Abdurahmon o’g’li; Saidov Olmos Shukir o’g’li; Mamatqulov Islom G’ayrat o’g’li

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 3, Pages 3071-3081

TBI is a complex pathophysiological process that includes primary and secondary brain damage that affects the structure and function of the nervous system. The incidence of TBI is 3 times higher than the population growth and the cost of treatment is more than 33 billion euros per year. Recently, there has been a growing interest in hypertonic saline solutions, which act in the same way, exerting an osmotic effect, increasing the movement of water from the tissues into the circulatory system. The present study was to study the efficacy and safety of using 7% NaCl in the treatment of intracranial hypertension in patients with isolated traumatic brain injury in the adult population. This group consisted of 35 patients with isolated traumatic brain injury at the age of 21-80 years (42.6 ± 13.2 years).