European Journal of Molecular & Clinical Medicine

Currently, the world community is faced with a new infectious disease that has not only medical, but also enormous socio-economic significance - the COVID-19 pandemic. (coronavirus disease 2019). The article discusses brief etiopathogenetic aspects of the new coronavirus infection. The role of some of the factors contributing to the development of nephro- and cerebrovascular disorders in COVID-19 is discussed. Results of work on coronavirus infection summarized foreign researchers

Various possible and non-mutually exclusive mechanisms may play a role in the development of ischemic stroke in patients with COVID-19. Long duration of mechanical ventilation (ALV) makes patients with COVID-19 who require invasive respiratory supportb more vulnerable to complications associated with the development of critical illness, including the risk of hypotension and inadequate cerebral perfusion; risk of relative hypertension leading to posterior reversible encephalopathy syndrome; the possibility of septic embolism in the event of a bacterial infection; the possibility of cardiomyopathy and a concomitant decrease in the left ventricular ejection fraction.

Objective of the article is to provide more comprehensive data of the prevalence of
neurological comorbid disorders and preexisting neurological disorders in patients with
COVID-19.
Method. We systematically searched the literature through Pubmed, based on the search of
combination of keywords: Covid 19, coronavirus, neurological disorders, stroke,
complications, neurorehabilitation.
Results. The increased biomedical interest in the problem of COVID-19 is due to its high
contagiousness, variable symptomatology, severe course and multiple organ failure in a
pandemic, the critical importance of the state of the nervous system. The manifestations can
be considered as direct effects of the virus on the nervous system, para-infectious or postinfectious
immune-mediated disease, and neurological complications of the systemic effects of
COVID-19.
Conclusion. The article deals with brief aspects of some factors contributing to the
development of neurological disorders in COVID-19 patients. The study results of coronavirus
infection of foreign researchers are summarized

The article provides a brief overview of the main problems and improvement of the
system of medical rehabilitation in the sanatorium-resort institutions (SRI) of the Kyrgyz
Republic, and also presents the results of treatment, i.e. the effectiveness of rehabilitation
measures.
In Kyrgyzstan, the initiated process of privatization of sanatorium-resort organizations
changed the form of ownership of more than half of state, departmental and public-owned
health resorts. In 2000, the share of state ownership in health resort organizations was 49.6%
(Data of the Statistical Committee of the Kyrgyz Republic, 2017).
We notice that for more than 20 years of independence of the republic, the
rehabilitation service has not been able to reach those former heights, there are internal and
external factors for this. Even the fact that today in the structure of the authorized body for
health protection (Ministry of Health) there is no department that would work on the
development of the rehabilitation service of restorative medicine, balneology and sports
medicine, which in turn caused the need to analyze and substantiate the activities of the
rehabilitation service in health resort institutions.

The rural population, in comparison with the urban population, has even fewer opportunities to receive dental care, since dental institutions, where the most qualified personnel and the latest equipment are concentrated, are located mainly in cities. Diversity of geographical and economic conditions of rural population, state of communications, accessibility of transport, etc. they aggravate the inequality of residents of different localities in the possibilities of obtaining dental care, so the specifics of the forms and methods of its provision in rural areas is primarily in the approximation of General dental care to the entire rural population.

Neuropathy of facial nerve (NFN) is actual problem in neurology, which is determined by the frequency of complications and the lack of a sufficiently effective treatment. In this research there are developed optimal methods of rehabilitation therapy of peripheral neuropathy of the facial nerve using acupuncture, therapeutic exercises, taking into account the peculiarities of clinical and functional changes depending on the timing of the disease. 64 outpatient records of patients (n = 64) aged from 16 to 60 years with a lesion of the facial nerve were analyzed. Patients were divided into two groups. The main group consisted of 34 patients who received acupuncture with electrostimulation together with pharmacotherapy. The control group included 30 patients who used pharmacotherapy. The use of A-IRT and ES together with pharmacotherapy made it more effective in restoring facial nerve neuropathy and its complications than using these methods separately from each other. Early use of these techniques in patients at the onset of the disease may be the cause of complete rejection of glucocorticoid, hormonal therapy, which makes it possible to optimize the rehabilitation of the facial nerve lesion based on the restoration of functions of the affected facial muscles.

The rural population, in comparison with the urban population, has even fewer opportunities to receive dental care, since dental institutions, where the most qualified personnel and the latest equipment are concentrated, are located mainly in cities. Diversity of geographical and economic conditions of rural population, state of communications, accessibility of transport, etc. they aggravate the inequality of residents of different localities in the possibilities of obtaining dental care, so the specifics of the forms and methods of its provision in rural areas is primarily in the approximation of General dental care to the entire rural population.

Relevance: The high prevalence, high risk of social maladjustment as a result of the consequences of acute cerebrovascular accident and, accordingly, one of the main causes of mortality gives cerebrovascular pathology a special status, as evidenced by numerous publications. the task was to identify in the studied patients the entire spectrum of clinical manifestations corresponding to the lesions of the brain structures supplied by the blood vessels of VBD and to determine the presence of a statistically significant dependence of clinical manifestations of COPD. As well as the identification of risk factors and their influence on the rehabilitation of patients with stroke in the vertebrobasilar system.
Patients with IS in VBD and COPD - 62 people (group I) - 29 men and 33 women aged 50 to 74 years (59.8 ± 5.8). Patients with IS in VBD - 64 people (group II). Of these, 31 were men and 33 were women aged 51 to 80 years (62.4 ± 5.4). All patients received traditional treatment in the most acute and acute periods of IS, patients with COPD received COPD treatment in parallel with traditional IS therapy. in group I, BMI averaged 29.3 ± 5.8 kg / m2, in men - 28.9 ± 6.3 kg / m2, in women - 29.9 ± 5.1 kg / m2 (the difference is not significant, p = 0.58), while 11 patients (17.7%) had a normal BMI, 1 patient (1.6%) had a body weight deficit, 26 patients (41.9%) had preobesity, 15 patients (24, 2%) had first degree obesity, 9 patients (14.5%) had second degree obesity. Accordingly, preobesity or obesity was recorded in 50 patients of group I (80.65%) (Figure 3.3)
And in group II, BMI averaged 28.7 ± 6.1 kg / m2, in men - 27.8 ± 5.7 kg / m2, in women - 30.1 ± 5.6 kg / m2 (the difference is not significant, p = 0.6), while 17 patients (26.6%) had a normal BMI, 3 patients (4.7%) were found to be underweight, 29 patients (45.3%) had preobesity, 8 patients (12 , 5%) had first degree obesity, 7 patients (10.9%) had second degree obesity. Accordingly, preobesity or obesity was recorded in 44 patients of group II (68.8%). In patients of group I, among the clinical manifestations of IS in PBS, ataxia prevailed, which occurred in 35 patients (56.5%), including hemiataxia, which occurred in 20 patients (31.3%). Paresis and paralysis of the limbs were detected in 31 patients (50%). Complaints about a subjective feeling of unsteadiness, instability in an upright position, and imbalance occurred in 25 patients (40.3%). Dysarthria also occurred in 25 cases (40.3%). Nystagmus was detected in 22 cases (35.5%), rotational dizziness (vertigo) - in 20 cases (32.3%), depression of consciousness - in 21 cases (33.9%). Symptoms such as hemianopsia and ophthalmoparesis occurred each in 14 cases (22.6%). Sensory disorders were detected in 12 patients (19.4%), autonomic disorders - in 8 patients (12.9%), diplopia - in 8 patients (12.9%), dysphagia - in 7 patients (11.3%) , aphasia and headache - 6 patients each (9.7% each), dysphonia - 7 patients (11.3%), confusion and visual agnosia - 4 patients each (6.5% each), respiratory failure - 3 patients (4.8%). There were also 2 cases (3.2% each) of amnesia, ignorance syndrome and a feeling of generalized weakness.

The article presents an analysis of domestic and foreign publications that analyze the organization of periodontal care for rural residents in different regions. Data on the quality and availability of dental care, risk factors for oral diseases are considered.

The rural population, in comparison with the urban population, has even fewer opportunities to receive dental care,since dental institutions, where the most qualified personnel and the latest equipment are concentrated, are located mainly in cities. Diversity of geographical and economic conditions of rural population, state of communications, accessibility of transport, etc. they aggravate the inequality of residents of different localities in the possibilities of obtaining dental care, so the specifics of the forms and methods of its provision in rural areas is primarily in the approximation of General dental care to the entire rural population.

The steering while sitting in the driver's seat is one of the most basic and important driving performances. The purpose of this study was to investigate the characteristics of sitting symmetry and steering accuracy of stroke drivers compared to healthy drivers, and to examine the correlation between them.Fifteen stroke drivers and fifteen healthy drivers participated in this study. Both group performed the large and small s-curve driving during five minute. Accuracy index (AI) was measured by comparing the performance line that drove along large s-curve and small s-curve (target line). Symmetry index (SI) was calculated by difference of right and left seat pressure.The steering AI of stroke drivers was significantly lower than that of healthy adult drivers (p <0.05), and the AI of small S-curves was significantly lower than that of large S-curves (p <0.05). The sitting SI of stroke drivers was significantly greater than that of healthy driver (p <0.05). Also, AI of stroke driver showed significant correlation with SI in both S-curve. However, healthy drivers had no significant correlation between SI and AI (p> 0.05). SI and AI are valid variables for evaluating the stroke driver's driving ability in off-road environment.