Online ISSN: 2515-8260

Keywords : ameloblastoma


Dr. Amitha J Lewis MDS; Dr. Shakthi Dorai MDS; Dr. Karen Boaz MDS; Dr. Srikant N MDS; Dr. Mohan Baliga MDS; Dr. Dharnappa Poojary MDS; Dr. Ankita Sharma MDS

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 3, Pages 381-389

Desmoplastic ameloblastoma (DA) a rare type of ameloblastoma, arises from the rests of dental lamina, developing enamel organ, epithelial lining of odontogenic cyst or from the basal cells of the oral mucosa. Clinically, DA develops as a slow growing, painless, bony hard swelling resulting in facial asymmetry. Histologically, it represents stromal collagenization or desmoplasia with small nests and strands of odontogenic epithelium. But the true biologic profile of DA is not well understood as they mimic fibro-osseous lesions clinico-radiographically. As DA is a rare entity,we aim to discuss three case reports of DA from a single institution which deserves pre-eminence owing to its distinct site, radiological and histological features, local aggressiveness and high chance of false clinical appearance. Desmoplasia is an inductive phenomenon occurring in the mesenchymal tissue of the head and neck region. The pathologist and the clinician should be aware of the concepts and the association with malignant transformation and spread of the lesion in order to deliver appropriate treatment.

Three Case Reports of Ameloblastoma with relevant clinico-radiographic and histopathologic correlations

Dr. Mohamed Abdulcader Riyaz SS

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 3, Pages 1269-1281

Ameloblastoma is one of the most common clinically significant tumor. It belongs to 1% of all oral tumors. Compared to maxilla, the mandible is qyite commonly affected (4:1). It affects both male and female population equally. The age at presentation is usually between 3rd and 7th decade of life. The usual clinical presentation is that of a slow growing asymptomatic intraoral swelling. There are four clinico-radiographic types of Ameloblastoma namely Unicystic, Multicystic, Peripheral (extra-osseous) and Desmoplastic. The Histologic types include Follicular, Plexiform, Acanthomatous, Granular, Basal cell & Desmoplastic. The unicystic type has three histologic variants namely luminal, intra-luminal and mural. This article is aimed at documenting three case reports of Ameloblastoma with histopathologic variations and correlating them with clinico-radiographic findings