Online ISSN: 2515-8260

Keywords : Pulmonary TB


Effect of Physical Environment and Prisoner's Behavior with the Implementation of Control Programs against the Incidence of TB in Makassar City

Haeruddin .; A. Rizki Amelia; Samsualam .; Ma'syari Arfah Tihurua

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 7, Pages 78-88

Purpose - To analyses the influence of physical environment and prisoner's behavior by the implementation of control programs on the incidence of TB in Makassar City.
Methods - Samples in this study were 90 people who were taken based on people having symptoms of pulmonary tuberculosis which included age, sex, level of education, occupation, and length of stay in prison, humidity, water temperature, room lighting, occupancy density, discharge behavior. Sputum / spit carelessly, smoking habits, cough / sneezing ethics, room contact with friends and implementation of control programs.
Results - The incidence of pulmonary TB ie from 90 respondents who suspected there were 41 respondents (45.6%). Variables that are significantly related to TB incidence are the discard phlegm on a reckless place variable, p = 0.008 (p <0.05). Discard phlegm on a reckless place against respondents affected by tuberculosis were 29 people (29%). Variable cough / sneezing ethics obtained p = 0.001 (p <0.05). More respondents were found when cough / sneezing was performed correctly on respondents who did not have tuberculosis in the amount of 25 people (52.1%). Variabel room contact with friends, p = 0.002 (p <0.05). Respondents of room contact with friends were bad for respondents who experienced tuberculosis, namely by 34 people (57.6%).
Conclusion - Discard phlegm on a reckless place, cough / sneezing ethics, room contact with friends are significantly related to TB incidence in Makassar City.

Analysis Of Risk Factors For Pulmonary Tuberculosis Incidence In Type-2 Diabetes Mellitus Patients

Hari Setiawan; Harun Iskandar; Himawan Sanusi; Syakib Bakri; Makbul Aman; Hasyim Kasim; Haerani Rasyid; Nur Ahmad Tabri; Arifin Seweng

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 3, Pages 1495-1499

Background:Incidence of pulmonary TB in type-2 diabetes mellitus patients is still high. Gender, age, nutritional status, duration of diabetes, blood glucose control, smoking habit, and HbA1c, are among risk factors that influence its occurrence. This study aims to analyze the risk factors that contribute to the incidence of pulmonary TB in type-2 DM patients in Makassar.
Methods:A survey analysis study at Wahidin Sudirohusodo Hospital. Hasanuddin University Hospital. and educational network hospital.on December 2019 until the desired sample reached. Sample collection using consecutive sampling. Data analysis using SPSS verse 22. Statistical analysis using pearson’s correlation. chi square test. and multiple logistic regression (backward method). Significant result if p value <0.05.
Results:Study included 225 type-2 DM patients. From study shows distribution of pulmonary TB in type-2 DM patients is 13.3%. Incidence of pulmonary TB was high in patient with underweight (OR=6.7 and p<0.05), duration of DM>5 years (OR=3.8 and p<0.05), and uncontrolled blood glucose (OR=2.7 and p<0.05). There was no significant correlation between gender (female 19 from 135, male 11 from 90 with p>0.05), age (age >60yo 15 from 92, age ≤60yo 15 from 133 with p>0.05), smoking habit (yes 10 from 84, no 20 from 141 with p>0.05) and HbA1c (A1c <7 was 0 from 7 and A1c ≥7 was 30 from 165 with p>0.05) with pulmonary TB incidence.
Discussions:Incidence pulmonary TB in type-2 DM patients according to BMI was significant (p<0.05) because condition of malnutrition can lowering the immune status by decreased the limphocytes production and immune proliferation also decreased of IFN-gamma and IL-2 level, and increased of TGF-beta. Incidence according to duration of DM was significant (p<0.05). Incidence according to blood glucose control was significant (p<0.05), DM and uncontrolled blood glucose can lead to an immune compromise condition, some of risk factors that also can contribute to infection disease.
Conclusion:There was significant correlation between underweight, duration of DM >5 years, and uncontrolled blood glucose with pulmonary TB incidence.