Online ISSN: 2515-8260

Keywords : Diagnosis


DIAGNOSIS AND TREATMENT ASPECTS OF SECONDARY NEUROENDOCRINE CHANGES IN ACUTE TWIN BRAIN INJURIES

Kuldasheva Yayraxon Mirzakarimovna; Xaydarova Feruza Alimovna - d.m.n., prof.; Kuldashev Kahramonjon Abdukhalilovich; Khakimova Zilola Kahramonjonovna; Inomova Gulmira Kakhramonjonovna

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 2, Pages 572-581

Nowadays, neuroendocrine symptoms following twin brain injuries (twin brain injuries) are more common and negatively affect the outcome of Brain Double Injuries by reducing the overall quality of life. However, research from the scientific literature suggests that neuroendocrine dysfunctions, particularly hypopituitarism, play an important role in the etiology of complications. It has been found that postoperative hypopituitarism has been a clinically common phenomenon in the last twenty years and is likely to contribute significantly to these disorders, given the parallelism of adenohypophysis among those following neuroendocrine changes associated with hypopituitarism other than cerebral palsy. In this our scientific study, we sought to explore hypothesized pathophysiological mechanisms based on neuroendocrine anomalies after a Brain Double Injury through an overview, improved on the basis of an analysis of early diagnosis and treatment aspects

“Diagnostic Tools For Early Diagnosis Of White Spot Lesions”

Dr. Arisha Izhar; Dr. Panchali Batra; Dr. Sanjay Miglani

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 2, Pages 680-695

In the recent years there has been an increase in the development of the newer technological methods to diagnose early demineralized lesion or white spot lesion. The diagnosis of white spot lesion is not always simple and might be subjective to the practitioner. 
Aim: This review aims to present an overview of the various qualitative and quantitative methods of detecting white spot lesion, including the novel technologies
Methodology: The most common method of qualitative assessment includes visual assessment and Photographic examination. Other qualitative methods are Fibre-Optic Trans illumination and digital fibre optic transillumination (FOTI and DiFOTI) and DiagnoCam. The quantitative techniques based on autofluorescence such as Quantitative
light-induced fluorescence (QLF), Light Emitting Diode (LED) fluorescence and Laser fluorescence such as Diagnodent, electronductivity such as Electrical Caries Monitor (ECM) , Optical coherence tomography (OCT) and some emerging technologies are discussed along with their advantages and disadvantages.
Result: These technologies enables the practitioners to diagnose white spot lesion timely so that their progression to fully developed carious lesion can be prevented.
Conclusion: The quantitative methods with suitable levels of sensitivity and specificity should be the preferred method but should be correlated with the qualitative methods to obtain a valid diagnosis.

Characteristic, Evolution And Influence On Epizootic Process Of Microorganisms In Biocenoses Of Livestock Farms

Pavel Rudenko; Aleksandr Strizhakov; Andrey Rudenko; Irina Bondareva; Elena Notina; Irina Bykova; Tatyana Dryemova; Vladimir Lutsay; Nikolay Ivanov; Nikolay Sakhno; Pavel Meshcheryakov

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 2, Pages 1865-1877

Background. The paper presents data on the variability and relationship of microorganisms in the biocenosis of livestock farms. Methods. The analysis of the available literature on the formation, operation, correction, and diagnosis of biocenoses of livestock farms. Results. It is shown that the animal organism is constantly exposed to the environment. A special place among the environmental factors affecting the animal body is microorganisms – causative agents of infectious diseases. Survey available of the literature on the evolution and relationship of microorganisms in different natural habitats. So, in the process of evolution to parasitism in tissues and organs of animals have adapted a variety of microorganisms: viruses, bacteria, fungi, protozoa, helminths, and arthropods. In the nature of a lot of evidence on the phylogenetic relationships of pathogenic microbes from nonpathogenic to the emergence in the evolution of new pathogenic forms of bacteria under favorable environmental conditions and organisms. Conclusion. Recommended livestock farms are to be regarded as ecosystems, artificially created by man. In them, there are special relationships between animals, protozoa, a diverse microflora, which are fundamentally different from those in vivo. In artificial biocenoses, the Association of conditionally pathogenic microorganisms that circulate in the economy can cause various diseases in farm animals.

MULTISPIRAL COMPUTED TOMOGRAPHY AS AN INSTRUMENTAL METHOD FOR SUBSTANTIATING THE PLACEMENT OF THE ACETABULAR COMPONENT OF THE HIP JOINT ENDOPROSTHESIS IN DYSPLASTIC COXARTHROSIS

Azizov Abror Mirxakimovich; Stupina Nadejda Vladimirovna; Xakimov Аkrom Dilshodbekovich; Valiev Odil Erkinovich; Nimatov Firuz Samadovich; Maxmudov Аrtur Аxmadovich; Tilyakov Xasan Аzizovich

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 9, Pages 2311-2317

to assess MSCT and clinical and radiological features of dysplastic coxarthrosis.

Review on Lipoma and Case Studies

Ashutosh Niranjan; Jagdish Mutreja

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 6, Pages 1336-1342

Lipomas are one of the commonest mesenchymal tumors in grown-ups which is moderate developing benevolent delicate tissue tumors. Albeit most lipomas are < 5cm in size, goliath lipomas >10cm have likewise been accounted for in various pieces of the body that infrequently happen in head and neck locale. Invading lipoma is an extraordinary mesenchymal neoplasm when a patient presents with an enormous, quickly advancing penetrating lipoma of the head and neck district, the chance of threat ought to be kept in mind. Lipomas are kind mesenchymal neoplasms of delicate tissue that can be found in any piece of the human body. Then again, their presence in the oral mucosa is somewhat phenomenal, with approximately 4% of the cases happening in the oral pit. The aim of this paper is to introduce the significance of finding and treatment of intraoral lipoma. Clinicians must be capable to recognize uncommon injuries, as intraoral lipomas, to provide appropriate treatment, in this manner guaranteeing solace and quality of life for the patient.

Assessment of Patient Health Condition based on Speech Emotion Recognition (SER) using Deep Learning Algorithms

Dr. DNVSLS Indira; B. Lakshmi Hari Prasanna; Chunduri Pavani; Ganta Vandana

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 4, Pages 1135-1147

Human Emotion detection either through face or speech became a relatively nascent research area. Speech Emotion Acknowledgment concerns the undertaking of perceiving a speaker's feelings from their discourse chronicles. Perceiving feelings from discourse can go far in deciding an individual's physical and mental condition of prosperity. These emotions can be used for further assessment of patient’s status for better diagnosis. This paper aims to categorize emotions in speech into four different categories which are happy, sad, angry and neutral. For this analysis, four different algorithms - the Support Vector Machine (SVM), Multi-Layer Perceptron (MLP), Random Forest (RF) and Convolutional Neural Network (CNN-1D) are developed. Detection of Emotion through speech of an individual might be a bit hectic, because of the dynamic changes in voice signal of the same person within a very subtle period of time. So, features like mfcc, chroma, tomez contrast and mel were extracted and given to the model in order to detect the emotions. Those features were given as input to the algorithms and the empirical results implicate that Convolutional Neural Network-1D performs well comparatively. RAVDESS database is chosen for the categorization. A good recognition rate of 89% was obtained from CNN-1D.

DIAGNOSTIC FEATURES OF CHOLEDOCHAL CYSTS IN CHILDREN

Erkin Yakubov; Nasriddin Ergashev

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 1955-1961

Abstract: The paper presents an analysis of the data of ultrasound, CT, MRCP and
intraoperative cholangiography in patients with bile duct cyst. Echographic data are
presented in 86 patients, CT in 61, MRCP in 8 and intraoperative cholangiography in 73
patients with this pathology. Ultrasound is a highly sensitive and informative screening
method for the diagnosis of choledochal cysts in children. To increase the specificity of
ultrasound with cysts of the common bile duct, a dynamic study of the contractility of the
biliary system after taking a "choleretic breakfast" is proposed. Currently, in the diagnosis
of pathology of the biliary tract, CT of the abdominal cavity and MRCP are effective noninvasive
methods, alternative to invasive ERCP. It has been established that the final
verification of the form of bile duct cysts, abnormal fusion of the pancreatic duct into the
cyst cavity is determined using MRCP and intraoperative cholangiography, which allows
you to choose the optimal method of surgical treatment.

ACUTE BACK PAIN: DIAGNOSIS AND TREATMENT

Bakhtiyar Gafurov; Zamira Babadjanova; Dilrabo Khalimova

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 2521-2525

Abstract: Back pain is a syndrome that can be associated with degenerative-dystrophic
changes in the spine, muscle damage and diseases, damage to the nervous system (the spinal
cord, its roots, and peripheral nerves), pathology of the internal organs of the thoracic and
abdominal cavities, pelvis, and mental disorders. The most common cause of acute back pain
is changes that occur when the muscles, ligaments, or joints of the spine are overloaded

ADVANCEMENT IN NANOTECHNOLOGY FOR RESTORATIVE DENTISTRY

N.E. Kaviya; Dr.Jayalakshmi Somasundaram; Dr.Anitha Roy

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 3295-3306

Nanotechnology is considered to be an upcoming technology. Nanotechnology in the field of dentistry helps in diagnosis, prevention and treatment. Nanotechnology incorporates the usage of nanoparticles less than 100 nm. The usage of nanoparticles in restorative materials has increased the quality and life of dental restorations resulting in better oral care and hygiene. The technology helps in modifying the existing restorative material in terms of physical, chemical and biological aspects to improve their quality. Nanotechnology uses nanoparticles which are synthesized naturally from plants and chemically. The usage of specific nanoparticles is based on the properties and cytotoxic actions. Conventional GIC (Glass Ionomer Cement) and composites have been modified and improved in numerous ways by the addition of different nanoparticles. The restorative materials with nanoparticles currently used are nanocomposites, nano glass ionomers, nano adhesives and endodontic sealers. Nanotechnology is paving the way for recent advances in nanomaterials innovations. The advances of nanoparticles are helping the future of dentistry and production of new developments of materials with high quality. The main drawback faced in using nanoparticles is the toxicity produced by the nanoparticles but the demand for nano based dental material preparation has increased so there is a need for new nanomaterials. The review article provides an overview of the advancement of nanotechnology in restorative dentistry.

Recent Advances Of Lab Testing Of COVID 19

Amirtha varshini; Leslie Rani. S; M.P. Brundha; Lakshminarayanan Arivarasu

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 3062-3069

A cluster of pneumonia cases infected with a completely unique coronavirus was reported in Wuhan, a city in Hubei province of China in December 2019. The acute respiratory illness is understood as coronavirus disease 2019 or COVID-19.3 The virus that caused this disease is designated severe acute respiratory syndrome coronavirus 2 or SARS-CoV-2. Workflows for COVID-19 laboratory diagnosis by screening and confirmation steps by molecular method have been designed and validated, with the utilization of synthetic nucleic acid technology. Diagnosis of COVID-19 depends on a mixture of epidemiological criteria, presence of clinical symptoms additionally as laboratory testing and clinical imaging based tests. COVID-19 includes analysing examples that demonstrate the present or past nearness of SARS-CoV-2. Tests for viral presence are utilized to analyze current ailment and to permit public health specialists to distinguish and contain flare-ups as fast as could reasonably be expected.The test can be done on samples obtained by various methods, including a nasopharyngeal swab , throat swabs, deep airway material via suction catheter or saliva. As evidenced by previous epidemics, including SARS and MERS, exceptionally delicate and explicit lab diagnostics are basic for case distinguishing proof, contact following, creature source finding, and productive and sane regulation measures. This study reviews the recent advances within the lab testing of covid 19

COVID -19 VS HANTAVIRUS- A REVIEW

Obuli Ganesh Kishore. S; Jothi Priya. A,; Lakshminarayanan Arivarasu

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 2248-2254

There is a rapid surge in research in response to the outbreak of COVID-19 which has taken the lives of many people.A detailed structured review of the corona virus could bring about any development in the field of research concerning the discovery of vaccines it treatment methods for COVID-19.Another virus called the Hanta virus that had originated in China was another pandemic which was controlled in the initial stages itself. Different articles and research journals were selected, analysed and computed for better understanding. The collection and analysis of data was done in the year 2020. A review of the epidemiology,clinical features,diagnosis,symptoms and treatment of corona virus and Hantavirus could help in advancements in its field of research. Also the comparison of economical impacts in the world during the pandemic virus attack can also be helpful to be economically prepared to face the crisis and reduce the chaos. But certain limitations that come across in this review had to be rectified for a proper result.But this review can be used for any quick reference regarding these deadly viruses.

Velscope- A Recent Examination Tool In Dentistry.

Neha .; Dr. Jayalakshmi Somasundaram

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 2475-2483

Oral cancer is a global health disease that has a major impact on an individual''s health, psychology and lifestyle. It is the 6th most common cancer in the world and has a high prevalence worldwide, and is found more in men than women. It is attributed to a myriad of causes which especially include tobacco smoking, alcohol consumption and chewing betel quid. Survival rates of oral cancer are very poor despite advances in therapeutic interventions. Detecting oral cancer at an early stage is believed to be the most effective means of reducing death rates. Thus arises the need for an important diagnostic tool which is able to detect pre-malignant and malignant lesions at an early stage. Treatment helps only for about 5 years after which recurrences are seen. The only way to reduce recurrences is early diagnosis. VELscope, also known as Visually-Enhanced Lesion scope, serves this purpose. It is an important diagnostic tool that uses an auto- fluorescence based imaging system to detect lesions and allows enhanced visibility of the premalignant and malignant lesions. It emits a harmless, non-invasive blue coloured LED fibre optic light that shines in the patient’s mouth. The fluorescent light is absorbed by normal tissues whereas neoplastic lesions lose fluorescence and become dark. This helps in quick and non-invasive diagnosis.

AWARENESS AND KNOWLEDGE ABOUT ARTIFICIAL INTELLIGENCE IN HEALTHCARE AMONG DOCTORS - A SURVEY

Samyuktha P S; Geetha R V; Jayalakshmi somasundaram

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 697-708

Artificial Intelligence is a progressive, rapidly developing field. It has the potential to ease diagnosis, treatment and care of patients. It is vital that medical professionals are aware about Artificial Intelligence and its scope in health care. Artificial Intelligence has the capability to ease diagnosis and care. The future of medicine is Artificial Intelligence based. A survey was carried to assess the awareness levels about Artificial Intelligence and its scopes in Healthcare. A questionnaire was circulated among medical and healthcare professionals. The total participation for the study was 100. The results were collected and tabulated to be analysed using SPSS windows version 20. There was an overall positive response from the participants. 92% believed that Artificial Intelligence is the future of medicine. Recent advancements have made it imperative that the healthcare workers be aware of Artificial intelligence and its scopes. Artificial Intelligence is reaching the medical field. It is a reality that a certain level of hyperbole seems to have taken over the discussion of Artificial Intelligence in healthcare. On one hand, healthcare industrialists and researchers highlight the need for high quality health data, on the other hand, physicians are still waiting for evidence of the usefulness of these tools and wonder who will be held responsible in case of an injury due to the tool, and the other ethical factors associated with it. It can be concluded that the participants had a moderate level of knowledge about Artificial Intelligence and its scopes, which can be improved.

VELSCOPE- A RECENT EXAMINATION TOOL IN DENTISTRY

Neha .; Dr. Jayalakshmi Somasundaram

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 359-366

Oral cancer is a global health disease that has a major impact on an individual's health, psychology and
lifestyle. It is the 6th most common cancer in the world and has a high prevalence worldwide, and is found
more in men than women. It is attributed to a myriad of causes which especially include tobacco smoking,
alcohol consumption and chewing betel quid. Survival rates of oral cancer are very poor despite advances
in therapeutic interventions. Detecting oral cancer at an early stage is believed to be the most effective
means of reducing death rates. Thus arises the need for an important diagnostic tool which is able to detect
pre-malignant and malignant lesions at an early stage. Treatment helps only for about 5 years after which
recurrences are seen. The only way to reduce recurrences is early diagnosis. VELscope, also known as
Visually-Enhanced Lesion scope, serves this purpose. It is an important diagnostic tool that uses an autofluorescence
based imaging system to detect lesions and allows enhanced visibility of the premalignant
and malignant lesions. It emits a harmless, non-invasive blue coloured LED fibre optic light that shines in
the patient’s mouth. The fluorescent light is absorbed by normal tissues whereas neoplastic lesions lose
fluorescence and become dark. This helps in quick and non-invasive diagnosis