European Journal of Molecular & Clinical Medicine

Background: Rheumatoid arthritis in children and their families can be a
significant health burden. They're linked to the risk of physical impairment, a
lower quality of life, and a lot of direct and indirect expenditures. The goal of this
study is to characterise the clinical spectrum of Juvenile Idiopathic Arthritis
(JIA) in children at Zagazig University hospitals, as well as the frequencies and
various patterns of JIA. Patients and methods: A cross-sectional research
comprised 120 patients with an average age of 16 years. From December 2017 to
December 2019, data on juvenile idiopathic arthritis was gathered during a twoyear
period. Complete blood count, reactive protein, ANA, RF, C3&C4, creatine
phosphokinase, and EMG were all performed. Management and treatment
strategies were implemented, and data on the outcomes was gathered.
Results:Females account for the majority of our rheumatological illness patients.In
our analysis, JIA was the most frequent rheumatological illness, followed by SLE
and lastly HSP.In our study, oligoarticular JIA was the most prevalent subtype of
JIA, followed by polyarticular and then systemic onset type.SLE is the second most
prevalent illness in our research, with the majority of patients being women.The
majority of individuals had cutaneous symptoms and a fever.The most commonly
utilised drugs were corticosteroids, cyclophosphamide, and mycophenolate
mofetil.HSP was the most prevalent kind of vasculitis found in our research.The
majority of patients are females, and those with severe GI symptoms and nephritis
got corticosteroids. Conclusion: The prevalence of rheumatological disorders in
children is underestimated, and there is a lot of overlap in diagnosis. Because
paediatric onset is less apparent than adult start, some patients have a significant
diagnostic lag. Early identification and proper care of these children is critical for
them to have a normal or near-normal life, particularly in patients with
rheumatological illnesses that cause chronic morbidity, such as JIA.