Keywords : post-menopause
European Journal of Molecular & Clinical Medicine,
2021, Volume 8, Issue 4, Pages 625-629
Background:Thyroid dysfunction is common in the general population, especially among
older women. The present study was conducted to assess thyroid function in postmenopausal
Materials & Methods:56 post- menopausal women and equal number of pre- menopausal
women were recruited and classified into group I and II respectively. All were subjected to
TSH estimation in RIA centre with Immunoradiometric assay kit. T3 and T4 were also
estimated if TSH level was abnormal. The sensitivity of TSH estimation was 0.05μIU/ml.
Normal level of TSH was taken as 0.5-4.5μIU/ml.
Results: There were 2 subjects in group I and 4 in group II with TSH level <0.5 μIU/ml, 50
in group I and 46 in group II had between 0.5-4.5 μIU/ml and 4 in group I and 6 in group
II had >4.5 μIU/ml. The prevalence of subclinical hypothyroidism was seen in 2 in group I
and 4 in group II and overt hypothyroidism in 1 in group I and 2 in group II. The
difference was significant (P< 0.05). The mean TSH level in group I was 3.02 μIU/ml and
in group II was 3.86 μIU/ml. The difference was non- significant (P> 0.05).
Conclusion: The prevalence of thyroid disorders especially hypothyroidism is more in
postmenopausal women than premenopausal women