European Journal of Molecular & Clinical Medicine

Effective pain management is critical for women after caesarean delivery, and
significant postoperative pain is related with persistent pain, higher opioid use,
delayed functional recovery, and postpartum depression. Intrathecal morphine is
the standard method for post-c-section pain, offering superior and extended
analgesia. Scheduled non-steroidal anti-inflammatory medications and
acetaminophen should be included in multimodal analgesia, with opioids reserved
for severe breakthrough pain. Wound infiltration and transversus abdominis plane
blocks are critical components of multimodal analgesia for patients who cannot
receive neuraxial opioids or who do not have appropriate pain management. While
analgesics may transfer to breastfeeding infants, transfer could be reduced by
careful drug selection and administration timing.