Online ISSN: 2515-8260

Keywords : Paediatric

Role of magnetic resonance imaging in paediatric brain infections

Dr.GurinderBir Singh,Dr.Poonam Ohri, Dr.Manmeet KaurSodhi, Dr.HiteshiGoyal, Dr. Manasi Kohli

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 4860-4866

Aims and objectives: To study the role of Magnetic Resonance Imaging in diagnosis of
paediatric brain infections, characterization of various patterns of brain involvement
and establishing the differential diagnosis along with role of Diffusion Weighted
Imaging and Apparent Diffusion Coefficient in Cerebral infections .
Materials and methods: 50 cases with suspected brain infection, whose age group
ranged from 0-14 years, referred to the Department of Radiodiagnosis and Imaging,
Government Medical College, Amritsar, were included in this study. The sequences
performed were T1W axial, T2W axial, coronal and saggital, FLAIR axial, DWI/ADC,
SWI,post contrast T1W in all patients and magnetic resonance spectroscopy wherever
required. MRI findings in all cases along with magnetic resonance spectroscopy, clinical
and biochemical findings (wherever required) were taken into consideration to arrive at
a diagnosis.
Results:Outof50patients,mostcommonpathologywastubercularinfectionsseen in 25
patients (50%), followed by 18 patients of pyogenic meningitis (36%), 5 patients of NCC
(10%) and 2 patients of viral encephalitis (4%). The most common finding in tubercular
infections was meningeal enhancement followed by tuberculomas, basal exudatesand
themostcommon complication was hydrocephalus. Themostcommon finding in pyogenic
meningitis was meningeal enhancement and the most common complication was
abscess. Neurocysticercosis lesions were parenchymal. Colloidal vesicular/granular
nodular stage was seen in 3 patients, vesicular in 2 patients and calcified in 1 patient.
Viral encephalitis was seen as areas of cerebral involvement bilaterally with restriction
on DWI/ADC seen in onepatient.
Conclusions: MRI due to its variable intensities in multiple sequences aided by contrast
enhancement helps the radiologist to arrive at an almost exact diagnosis. Italso
drawssupportfromassociatedclinicalfeatures, lesion-staging, complicationsand number
(single or multiple) of the lesions. Thus it scores over CT and ultrasound as basic
modalities for imaging infective disease of brain inchildren.


Dr Anshu Sood

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 11483-11488

Background: Chronic suppurative otitis media (CSOM) is a chronic inflammation of the middle ear and mastoid cavity, which presents with recurrent ear discharges or otorrhoea through a tympanic perforation. The present study was conducted to assess factors affecting the surgical outcome in tympanoplasty in children.
Materials & Methods: 54pediatric patients of persistent perforation of the tympanic membraneof both genders were enrolled. Age at time of surgery, state of contralateral ear, previous adenoidectomy, cause of perforation, size of perforation, infection at the time of surgery, state of mucosa, age at first occurrence of perforation, presence of craniofacial dysmorphia, and surgical technique were recorded.
Results: Out of 54 patients, boys were 34 and girls were 20. Success rate was seen in 30 and failure in 24 cases. Contralateral ear normal in 22 and 18 and CME in 8 and 6. Cause of perforation was infection in 24 and 19, previous adenoidectomy was not done in 17 and 14 and done in 13 and 10, size of perforation was <50% in 16 and 16 and >50% in 14 and 8, state of mucosa was normal in 25 and 17, surgical technique was onlay in 24 and 18, otorrhea at time of surgery was absent in 28 and 20 and present in 2 and 4 in success and failure cases respectively. The difference was significant (P< 0.05). Closure of perforation was seen in 50. Hearing gain was seen in 32 and no gain in 22. Air-filled space was adequate in 46, otitis media with effusion in 6 and partial atelectasis in 2 cases. The difference was significant (P< 0.05).
Conclusion: Study mitigates against delaying tympanoplasty type I in paediatric patients.