European Journal of Molecular & Clinical Medicine

Varicose veins are veins that have become enlarged and tortuous. The term commonly refers to the veins on the leg. Endovenous laser therapy (EVLT) is a popular treatment for varicose veins. The study aimed to assess improvement the occlusion rate in the treatment of patients with varicose veins. Patients and methods: this study involved 18 patients with lower limb varicose veins presented at Zagazig University Hospital. All patients were examined clinically to identify symptoms and signs related to venous diseases and duplex ultrasonography were performed. Evaluation was done after one week, one month, 2 months and 3 months following treatment. Results: All patients had improvement in VCSS after EVLA during the first, second and third follow up visits when compared with preoperative scores. The VCSS ranged from 5 to 15 before the procedure, with a mean of 8.89, ranged from 1 to 6 at the first follow up visit with a mean of 3.4, ranged from 1 to 5 at the second follow up visit with a mean of 2.5 and ranged from 0 to 4 at the third follow up visit with a mean of 1.6. CIVIQ in the legs of studied group: Pre-operative was14.42 ± 7.29 while after 6 month was 7.64 ± 4.62. Only Ecchymosis in 2 limbs (6%), Paresthesia at leg in 3 limbs (9%), Phlebitis 4 limbs (12%),Skin burn in one limb (3%)and Incomplete occlusion in one patient(4%). Conclusion: Higher energy EVLA of varicose veins showed faster recovery attributable to the decreased pain, immediate ambulation and faster return to everyday activities. Patients experienced symptom relief after the procedure with decrease the VCSS and CIVIQ in both.

LASERs have been used in the field of dentistry for more than 40 years. Their wide range of application and reduced pain perception and bloodless procedure makes them readily acceptable for clinical practice. They have multiple advantages such as reduction in treatment duration, increase patient’s level of acceptance that helps orthodontists to improve on their treatment efficiency, improve smile esthetics by reducing patient discomfort. Pertaining to orthodontics, LASER application includes pain reduction, alternate to routine etching and bonding techniques, accelerating tooth movement, debonding of brackets, numbering of brackets, increase implant stability a, bracket mesh designing, reduction in rate of demineralization and soft tissue procedures namely, frenectomy, gingivectomy, exposure of impacted teeth, operculectomy, papilla flattening, etc. Like any other technique, LASERs have their own disadvantages. This review article is about the use of LASER in orthodontics, their effects on different tissue, mechanism by which it is formed and various types of commercially available LASERs and their uses clinically.

Objective: To test the diagnosis of oral leukoplakia with diode laser.
Materials & methods: Throughout this investigation we found five cases of oral leukoplakia that were validated through biopsy then diagnosed using laser diode.
Results: Diode laser offers pain free and fast tissue repair resulting from the procedure. The time of recovery lasted from 7 days to 30 days well after laser cure and no resection from 2 years well after research.
Conclusions: The diode laser seems to be an effective means of handling contaminated wounds and helps avoid malignancy by treating oral leukoplakia.

This study examines the antiangiogenic effect of activated naked gold nanoparticles (AuNPS) in dorsal skinfold window chamber rat model after laser coagulation of dorsal blood vessels, to investigate whether the antiangiogenic effect of AuNPs can inhibit reperfusion and neovascularization of photocoagulated blood vessels in an animal model.This study includes 2 groups, each group contains 10 rats, laser group (control group), and AuNPs group. After laser photocoagulation of dorsal blood vessels through the dorsal window chamber fixed on the dorsum of albino rats, the structure of blood vessels and flow dynamics were documented with color digital photography to evaluate photocoagulation and reperfusion. The laser sessions and injection of AuNPs to the epidermal side of the window were twice weekly for 2 weeks. In the laser group (control group), 18 out of 20 photocoagulated blood vessels reperfused within 4-12 days with reperfusion rate 90%. In AuGNPs group 9 out of 22 photocoagulated blood vessels reperfused within 4-12 days with reperfusion rate 40%. Laser activated naked gold nanoparticles have significant antiangiogenic effect, with minimal side effects detected with local use.