Online ISSN: 2515-8260

Keywords : Benign breast disease

A cytomorphological study of non-malignant breast lumps in a hospital set up

Nabaneet Majumder, Jayanta Debnath, Swarupa Chakma

European Journal of Molecular & Clinical Medicine, 2023, Volume 10, Issue 1, Pages 460-467

Background- Fine needle aspiration cytology (FNAC) is one the most convenient and inexpensive tool for preoperative assessment of breast lumps. It has gained popularity due to its fast and easy approach and can be performed with very little complications. In other words, FNAC may save anxiety, trauma, time and money. Nevertheless, in FNAC of breast lumps paucity of aspirate material or morphological overlapping features make it challenging for cytopathologists in reporting.
Materials and methods- It is a prospective study done from September 2021 to September 2022. A total of 98 FNAC cases, diagnosed as non malignant breast lesions were included in this study. The study was done at department of pathology, Tripura Medical College and Dr. B R Ambedkar Teaching Hospital, Hapania, Tripura. Some suspected infective cases with purulent material were sent to microbiology department for culture sensitivity testing and Zeihl-Neelson testing to rule out Acid Fast Bacilli. Reporting was done using IAC standardized reporting system for breast lesions. They have categorized the breast lesions into C1 to C5 (C stands for Code).The collected data were entered in SPSS (Statistical Package for Social Sciences Inc, Chicago, IL, USA) version 16.0.
Results- A total of 98 non malignant breast lesions from all the female patients were included. Most of the cases (61.2%) presented in 2nd and 3rd decade and maximum cases i.e. (35.7%) were seen between 20-30 years of age. The mean age of patient was 31.99±11.7. Majority the palpable breast lumps in this study were ≤5 cm (80.6%). Right sided breast lumps were seen in 50.0% cases. Among all the quadrants, upper-outer quadrant presented with most common site for breast lesions (48%). Among the non-malignant breast lesions under category C2 and C3, fibroadenoma presented with highest number of recorded cases (39.8%) and followed by fibrocystic change (32.7%).  Females presented with benign breast disease residing in urban areas were (56.1%).
Conclusion- Fine needle aspiration cytology is one of the best technique to evaluate breast lumps used in a country like India with limited resources. It is minimally invasive, rapid and effective method for preoperative diagnosis to relieve the anxiety of patient and also for post-operative follow up of breast lumps to ensure the recurrences. FNAC has some pitfalls, both false-positive and false-negative results can occur, which can be reduced by experience and expertise of cytopathologist. The triple assessment method by clinical, radiological and pathological examination is a standard approach in the evaluation of breast lumps.

Clinical profile of patients with benign breast disease

Dr. Avinash Chandra S

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 1, Pages 272-276

The nomenclature of benign breast disease is very confusing.This is because over the last
century a variety of clinicians and pathologist have chosen to describe a mixture of
physiological changes and disease processes according to a variety clinical, pathological and
aetiologicalterminology. The study includes patient attending surgical out patient department
and admitted to surgical wards with breast lump during the study period. Most of patients
presented in OPD with complaints of breast lump 66 (60%) followed by patients presenting
with lump and pain of 33(30%). Some patient show engorgement of breast 8 (7.2%).Few
Patients also presented with lump, pain and discharge 3 (2.7%).

Histopathological study and management of benign breast disease at a tertiary care hospital

Dr. Avinash Chandra S

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 1, Pages 277-283

Benign breast disease is primarily a phenomenon seen in reproductive age group. They are
thought to be largely hormone induced. Benign breast disease is 4-5 times more common then
breast cancer. The study includes patient attending surgical outpatient department and
admitted to surgical wards with breast lump during the study period. Most of the patients
underwent excision-85 patient (77.27%) followed by microdochotomy-4 (3.63%)and I & D-4
(3.63%).Simple mastectomy also done in 4 (3.63%) patients. Wide excision biopsy was done
in 3 (2.72%) patient. Majority of the patients 90 patients (81.81%) did not have any postoperative
complications, whereas 12 patients (10.90%) had discharge from wound and 5
patients (4.54%) had wound gape due to infection.

Characteristics of surgically treated benign breast disease

Hemanth Gudur, Shanker Dharmaraj Basa

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 1, Pages 495-499

Introduction: Benign breast condition refers to a lump, cyst, or nipple discharge (fluid) of the female or male breast that is not cancerous. Benign breast conditions are generally caused by a number of factors. Those factors include the makeup of breasts (fatty tissue vs. dense or thick tissue), age, hormone problems.
Methods and Materials: This is a prospective study and observation study conducted in the Department of General Surgery at Prathima Institute of Medical Sciences over a period of 1 year.All patients who underwent surgery for benign breast disease were included. Patients who did not undergo surgery for benign breast disease were excluded. All the data were collected in predesigned proforma by observation of the files and operation notes of patient who underwent surgery for benign breast disease. The files were retrieved from the case sheet and histopathological examination reports were obtained from the department of pathology and relevant information were noted.
Result: In our study, most of the patients were 21-30 years i.e., 38 out of 70 (54.2%), followed by 10-20 years, i.e., 17 out of 70 (24.2%) and least were 1 (1.4%) belongs to 51-60 years.Patients with lump in left breast were more in number (31) than those with lump in right breast (29). Bilateral lump presentation as the least common 10 (14.2%) patients. In our study, 42 was firm 60% followed by 9 were soft while 19 were hard in consistency.Fibroadenoma was the most frequently diagnosed lesion, followed by fibrocystic change. Epidermoid cyst was the third most commonly diagnosed. Other histological diagnoses were fat necrosis, lactating adenoma and tuberculosis of the breast.
Conclusion: Benign breast disorders are a group of conditions that are commonly managed by surgeons. Benign breast pathologic conditions rarely increase the risk of malignancy. As knowledge of benign breast pathologic conditions improves, many conditions can be managed without the need for open surgery. Collaborative care models including nurse practitioners can improve patient experience and education about their breast health.