Online ISSN: 2515-8260

Keywords : Blood components

An audit of the use of blood components in acute systemic infections and its correlation with clinical outcome in children

Sunil G Lawand, Parvathy Balkrishnan

European Journal of Molecular & Clinical Medicine, 2023, Volume 10, Issue 1, Pages 227-230

Background: The present study was an audit for evaluating the use of blood components in acute systemic infections and its correlation with clinical outcome in children.
Materials & methods: A total of 100 subjects were enrolled. Any preterm and term neonates admitted to the NICU and Neonatal Intermediate Care Unit (NIMC) and receiving any transfusion, i.e., fresh frozen plasma (FFP), red cell concentrate (RCC), platelets, and exchange transfusion were included. The data was collected from the medical records. Patients were categorized according to the classification of neonatal conditions by the International Classification of Diseases 11th Revision (ICD-11).
Results:A total of 100 subjects were enrolled. Out of 100 neonates, 70 neonates received fresh frozen plasma. The platelet concentrate was received by 32 individuals whereas whole blood was received by 12 subjects. Transfusion data for all of the components yielded a statistically significant result. A condition chewing blood products are sepsis (82), meningitis (4). The other disorders comprise of 11 patients.
Conclusion: Over the few decades, there has been an increasing focus on use of blood components in managing pediatric patients with acute systemic infections. The exact ontogeny of individual components of the hematological system, and how they interact and drive the response to infectious agents, is of particular importance in understanding paediatric systemic infections. Hence; further studies are recommended

Quality control of blood components-a step towards efficient supply of blood products

Dr. Sachin Sharma, Dr. Ashok Yadav, Dr. Radhika Rai, Dr. Yogesh Pawde

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 1, Pages 333-336

Objective: The aim of study was to ensure supply of safe and efficient blood transfusion to
patient and to prevent Transfusion Transmitted Diseases.
Methods: The present study included data of routine monthly analysis of whole blood and
blood components which was collected from archives of blood bank from the period of 1st
January 2018 to 31st December 2019. Data was collected for the above mentioned period in
which blood was collected from 2520 healthy donors in sterile single, double or triple blood
bags with anticoagulant Citrate Phosphate Dextrose Adenine 1 (CPDA 1) after taking written
Result: Mean volume was 65.5 mL with range of 50-70 mL. Mean WBC contamination was
1.4×108/unit with a range of 0.15-5.5×108/unit. Mean RBC contamination was
0.077×1012/liter with a range of 0.05- 0.14x1012/liter.
Conclusion: Quality indicators should be well-defined, regularly monitored and properly
documented. Quality Control is an important tool to ensure maximum benefit to patient with
minimum cost and maximum advantage and minimizing requirement of transfusion to patient
and Prevention of risk of Transfusion Transmitted Diseases.