European Journal of Molecular & Clinical Medicine

Intravesical prostatic protrusion (IPP), a unique anatomical configuration has recently become a very significant component in the evaluation of BPH patients. Hence the present study aimed to evaluate the outcome of initial trial without catheter in Benign prostatic hyperplasia patients with IPP of different grades presented with acute urinary retention.
Materials & methods: The retrospective study conducted at Urology unit, Department of General Surgery, Agartala Government Medical College, Agartala from September 2018 to January 2022. Patient fulfilling the inclusion criteria were included in the study. Data sheet was completed where the patient’s demographics, IPSS, PSA, total prostate volume, IPP and its grade, peak flow rate of voided patients, PVRU was recorded and analyzed.
Results: Mean patient age was 69.76±9.54 years (range 52 to 87) in group A, 67.80±7.70 years (range 54-82) in group B and 66.23±8.84 years (range 51-81) in group C. Mean value of IPP was greater in group C with statistically significant result with p value <0.01 comparing group A and C. Correlation between IPP with other pre-treatment parameters show significant results with TPV, TZV, TZI, QoL, PUFR & PVRU.
Conclusion- IPP is a helpful indicator for determining whether a voiding trial after ARU was successful. A trial without a catheter may be advantageous for BPH patients with grade 1 IPP. Patients with grade III IPP, on the other hand, are less likely to do so and would need a more thorough surgical intervention.

Introduction: Establishing or ruling out the diagnosis of carcinoma of prostate has been
a challenging task for pathologists for many years .it was an observational study where
patients who underwent TURP procedure were studied. The present study is an attempt
to understand the histopathological spectrum of prostatic lesions and study the
demographic distribution of various prostatic lesions.
Methods: The present study includes 125 cases of prostate specimen from January 2018
to September 2021 received in the post graduate department of Pathology, Tripura
Medical College. H and E stained sections were examined. The relevant clinical details
pertaining to age, clinical complaints and microscopic details are analyzed and
compared with other similar studies.
Result: Total 125 case were studied among which 69 (55.2%) cases were found to be
consistent with BPH and 24 cases were found to be malignant lesion (19.2%). 24 cases
were found to be BPH with associated prostatitis like features, consistent with benign
prostatic lesion. High grade Prostatic Intraepithelial lesions were seen in 8 cases (6.4%).
Out of the 24 malignant cases, majority had Gleason score between 8-10. Perineural
invasion was seen in 10 out of 24 malignant cases (41.6%). All malignant lesions were
adenocarcinoma and 20 were incidental carcinoma which accounted for 16% of all
prostatic lesions. Serum prostate specific antigen levels were available in 24 cases of
prostatic adenocarcinoma cases. 21 out of 24 cases had serum prostate specific antigen
levels greater than 10 ng/ml. (87.5%). Grade Group 4 had the maximum number of
cases i.e 45.8%. Out of 125 cases, 89 (71.2%) cases were from urban areas and 36
(28.8%) cases were from rural areas. All the 24 cases with prostatic adenocarcinoma
were from urban areas.

Objective: To examine the potential clinical implications of the voiding position in asymptomatic Indian men.
Materials and methods: Men between the ages of 20 and 70 were included in our prospective research of men. The subjects were required to complete a 3-day voiding diary, and uroflowmetry was performed in accordance with our department's normal methodology.
Results: Qavg and Qmax were 17.5 and 28.7 mL/s on average. The typical V24 and F24 were respectively 1653.7 mL and 6.5. The biggest single voided volume (r = 0.308, P = 0.002), the smallest single voided volume (r = 0.500, P = 0.001), the daytime voided volume (r = 0.378, P = 0.001), the nighttime voided volume (r = 0.533, P = 0.001), and Vavg (r = 0.704, P = 0.001) were all positively correlated with the mean V24. PVR (r = 0.415, P<0.001), night time frequency (r = 0.353, P<0.001), and voiding frequency (r = 0.345, P < 0.001) were all strongly correlated with mean age.
Conclusion: The uroflowmetry parameters of elderly men are significantly influenced by the voiding position. It was discovered that voiding while sitting was ideal for elderly men, but it was impossible to tell what effect the voiding position had in healthy young men. To further understand this problem, more investigation is required.