Online ISSN: 2515-8260

Keywords : UTI


Prevalence Of Asymptomatic Bacteriuria In The Three Trimesters Of Pregnancy In A Tertiary Care Hospital Of North India

Dr Gaurav Kumar; Dr Ranvijay Singh; Dr Snehanshu , Shukla; Dr Anand Shukla; Amit Kumar Singh; Dr Satyajeet Verma; Dr D.K. Singh

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 7, Pages 1768-1774

Introduction:Asymptomatic bacteriuria in pregnancy can lead to complications like urinary tract infections (UTI), pyelonephritis, pre-eclampsia, toxaemia, low birth weight, intra uterine growth retardation, preterm labour, preterm premature rupture of membrane and post-partum endometritis. There is insufficiency of data regarding prevalence, causative organism and antibiotic sensitivity pattern in all three trimesters of pregnancy. Thus to prevent the complications screening for ASB has been suggested for all pregnant women attending antenatal clinics.
Aims:To determine the prevalence of asymptomatic bacteriuria in three trimesters of pregnancy at a tertiary care hospital of north India.
Materials and Methods: All asymptomatic pregnant females attending the antenatal clinic at district hospital of Barabanki were included in the study except those with symptoms of UTI such as dysuria, urgency, frequency & fever. Isolation and identification were done as per standard laboratory protocol. Antimicrobial susceptibility test was done as per CLSI guidelines.
Results: In this study, 900 pregnant females were screened for ASB out of which 87 (9.6%) were culture positive.The prevalence of ASB was 10.24% (39 out of 381) in primigravida, 10% (30 out of 300) in secundigravida and 5.55% (9 out of 162) in gravida 3 and 15.78% (9 out of 57) in gravida 4. Theculture positivity associated with the gestational agewas found to be 24.13% (21) in the 1st trimester, 34.48% (30) in the 2nd trimester and 41.37% (36) in the 3rd trimester. Majority (75.87%) of the culture positive isolates were gram negative viz, E.coli(34.48%), Klebsiella(24.14%) and Proteus(17.24%).
Conclusion: Routine antenatal urine cultures should be done periodically in every trimester in order to screen ASB and appropriate treatment should be provided along with general health education regarding personnel hygiene and habits to avoid further complications specially to the 1st trimester OPD patients as they are found to be the most affected group in this study.

Describing the Major Pathogens Causing UTI Among Patients, The Prevalence Of UTI and Establish Susceptibility Pattern of Antimicrobial Resistance

Dr. Aarti Akhand, Dr. Ramanath Karicheri

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 4909-4913

Background & Method: The Study was carried out among UTI patients in Index Medical College and Associated Hospital at Khudel Village in Indore that gives healthcare to surrounding area and is used as teaching and referral hospital. The study targeted both male and female outpatients and inpatients presenting with symptoms and signs of UTI which include dysuria, polyuria, fever, nausea, and flank pain were sampled for this study. Baseline demographic data including age, sex, level of education and risk factors such as catheterization, history of UTI, also out and in patients were also collected.
Result: The 385 urine specimens processed, 112(29.0 %) showed significant growth whereas the majority of the urine samples that is 273 (71 %) showed no growth. Fresh samples were collected from patients by mid-stream catch method in sterile universal bottles (Plate 1). The assessment of associated risk factors showed gender (χ2 = 0.116, P=0.0412), age group (P=0.0120), History of UTI (χ2 =0.555, P=0.004) and symptoms of UTI (χ2 =0.895, P=0.017) were significant. Level of education (χ2 =2.742, P=0.523) and catheterization (χ2 =0.17, P=0.054) were not significant.
Conclusion: The prevalence of UTI in Index Hospital was 29.1 %. E. coli was the highest among 120 the isolates. Females had a higher (62.1 %) prevalence of UTI than males (37.9 %). Urinary tract infection was associated with the previous infection and with patients who had the history of catheterization. All isolates were sensitive to nitrofuratoin, cefotaxime and amoxicillinclavulinic acid. High resistance was observed in gentamicin, nalidixic acid, ampicillin and cotrimoxazole. In the 120 isolates were resistant for more than two antibiotics were recorded in 108 (90 %) isolates. Antibiotic susceptibility patterns of all patients with bacterial uropathogens will reduce multidrug resistance.

PREVALENCE AND ANTIBIOTIC SENSITIVITY OF MICROORGANISMS CAUSING UTI IN DIABETICS

Ram Naresh Sharma, Ahsan Hamidi, Satyendu Sagar

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 11508-11513

Background:Urinary tract infections (UTI) are among most prevalent illnesses seen in diabetics. To reduce the morbidity of symptomatic infection, early diagnosis and treatment is indicated. This study was done to assess the prevalence of UTI in diabetics, responsible organism & antibiotic sensitivity.
Materials and Methods: A total of 100 diabetics >18 years of age reporting to department of Microbiology were studied. Urine examination was done for isolation and antibiotic sensitivity testing.
Results: Prevalence of UTI was 39 %. E. coli followed by Enterococcus and Klebsiellaspp were most commonly isolated. These were sensitive to amikacin, imipenem and linezolid.
Conclusion: Isolation and antimicrobial sensitivity testing of uropathogens is vital in diabetics with UTI.

Study of subclinical Vitamin A deficiency in suspected group of children by conjunctival impression cytology at a tertiary care centre in South India

Dr. Vasanth Kumar D. L, Dr.Navya, Dr. Bheemaraya Shivasharana, Dr. Ravindra B Patil

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 1, Pages 999-1006

Introduction: Vitamin A is required throughout the lifecycle.Vit A deficiency and
Xerophthalmia occur throughout much of the developing world and are linked to undernourishment
and complicated by illness. In developing countries, it is estimated that 5 lakh
preschool children become blind every year owing to Vitamin A Deficiency and many of
them will die because of increased vulnerability to infections, especially measles, diarrhea
& pneumonia. In southern districts of Karnataka, including Shivamogga, the burden of
malnutrition, respiratory infection, diarrhea, measles and post-measles infections are high
leading to significant morbidity and mortality. Majority of the studies related with Vitamin A
deficiency are mostly concerned with clinical signs and symptoms of vitamin A deficiency.
However subclinical Vitamin A deficiency is often missed. The present study is aimed to
detect subclinical Vitamin A deficiency in children at risk, so that supplementation of
Vitamin A in early stage may bring down the burden of preventable morbidity and mortality.