European Journal of Molecular & Clinical Medicine

Background: Poisoning in children is a worldwide epidemic, and there is no region in the world that is immune to this catastrophe. In paediatric practise, it is one of the most frequently encountered situations that could have been avoided. Both the cause of poisoning and the type of poisoning can vary greatly from one region of the world to another. This is because the availability of poison to children is influenced by a variety of factors, including population, socioeconomic standing, level of education, as well as local beliefs and practises.
Martial and Methods: A future hospital-based study in India with a prospective design. Over the course of three years, beginning in June 2021 and ending in June 2022, children hospitalized to Sambaram Institute of Medical Sciences and Research with suspected acute poisoning were the subjects of a study that was designed as a prospective investigation. A parent or other relative who was present throughout the interview provided background information about the youngster.
Results: 210 children were found to be suffering from acute poisoning. There were 125 males, and there were only 85 girls. In 110 of the instances, household goods were involved, while pharmaceuticals were involved in 62, toxic plants were involved in 21, agrochemicals were involved in 13, and other substances were involved in 4.
Conclusion: In conclusion, I would like to offer some suggestions for some strategies that can assist to minimize the prevalence of childhood poisoning in India, in addition to the morbidity and death associated with it. Keep the containers of kerosene oil securely sealed and out of the reach of youngsters at all times. Do not keep kerosene oil in soft drink bottles. Make people aware of the potential risks associated with vomiting after consuming kerosene oil. Keep any agricultural chemicals in a secure location. Instruct the general public on how to properly dispose of unused medication.

Background: The prevalence of renal dysfunction has been reported to vary from 14-50% in
patients with cirrhosis. The prevalence is estimated to be approximately 50% among patients
with cirrhosis and ascites and 20% of patients with advanced cirrhosis admitted to the hospital
3,4. The wide range in prevalence is likely due to different study populations and varying
definitions of renal dysfunction. Patients with HRS who fail to respond to medical therapy or
those with severe renal failure of other etiology may require renal replacement therapy.
Simultaneous liver kidney transplant (SLK) is needed in many of these patients to improve
their post-transplant outcomes. However, the criteria to select patients who would benefit from
SLK transplantation are based on consensus and lack strong evidence to support them. Heath
care system has evolved over the last decade and newer drugs are available for the management
of complication of cirrhosis. We attempt to study its impact on course and outcome of acute
kidney injury. Also few of the patients could possibly be on the antiviral drugs for hepatitis B
and hepatitis C. If these patients are admitted they will be included in study and we would study
the effect of the effect of this drug on acute kidney injury and vice versa. Hence, the present
study was conducted to study clinical profile of patients with acute kidney injury in liver
cirrhosis.