European Journal of Molecular & Clinical Medicine

Introduction:  Cerebrovascular accident (CVA) or stroke is defined as an abrupt onset of a neurologic deficit that is attributable to a focal vascular cause. Cerebrovascular accidents (CVA) can be classified into two major categories: about 87% of strokes are ischemic, the rest being haemorrhagic.Studies have demonstrated the fact that primary neurologic abnormalities may produce ECG changes without any myocardial lesion.
Aim: To study the various types of ECG changes in patients of cerebrovascular accidents. To compare the ECG changes in patients of haemorrhagic and ischemic cerebrovascular accidents.
Material and methods: This present study was carried out in 50 cases diagnosed as CVA admitted in the Department of Medicine in a tertiary care hospital of Punjab(North India) after obtaining their informed consent.All patients with CVA of less than 10 days duration admitted in the Department of Medicine were included in this study. A detailed history was taken and patients were selected as per inclusion and exclusion criteria. Along with other investigations 12 lead ECG tracing on admission and after 72 hours of stroke onset was performed. The ECGs were analysed for the occurrence of arrhythmias, ST-T segment changes, changes in various intervals and ectopic beats.
Results: In our study population of 50 patients, 38 (76%) patients were having ischemic stroke and 12 (24%) patients were having haemorrhagic stroke. In our study, prolonged QTc was the most common ECG abnormality.In our study, ST segment changes were most commonly noted in ischemic stroke.12% of patients with ischemic stroke had ST depression and 2% had ST elevation. In our study, sinus tachycardia was the most common rhythm change observed in both ischemic CVA(26%) and haemorrhagic CVA(36%) followed by sinus bradycardia.
Conclusion: This study showed male predominance in stroke cases. Cerebral infarction was more than haemorrhage.ECG changes were more commonly associated with ischemic stroke as compared to haemorrhagic stroke.Cardiac disturbances are diverse and frequent in the setting of acute neurological injury.Understanding of these ECG changes occurring in patients with CVA is important because it may lead to erroneous judgment of assigning these patients as CAD.These patient should be evaluated for cardiac injury and treated only if necessary.

Introduction: Stroke is associated with up to 5.54 million deaths every year, two thirds of which occur in resource poor countries. Non-contrast computed tomography (CT) scan is the gold standard for distinguishing stroke sub-types. It is cheaper than Magnetic Resonance Imaging (MRI) but is still expensive and inaccessible for most resource poor settings. To overcome these difficulties and to enhance clinical bedside diagnosis, clinical stroke scores have been developed. Hence, the present study was undertaken to assess accuracy of Siriraj score system in classifying clinical type of stroke and correlation of Siriraj score diagnosis with CT scan.

Background: Stroke is the top cause of death and one of the leading causes of long-term
disability all over the world. hsCRP levels evaluated shortly after a stroke have been
demonstrated in studies to predict complementary elements of outcome. There's a
chance that high hsCRP levels are linked to the severity of cerebral tissue damage. We
wanted to see how high hsCRP levels were in people who had a cerebrovascular
accident. The goal was to see if there was a link between the level of hsCRP and the
severity of the stroke and the outcome.
Material and Methods: Patients hospitalised to a tertiary care hospital's (Narayana
Medical College Nellore) medical ward and medical ICU were studied. It was a crosssectional
investigation. The study involved a total of 100 patients who had a stroke and
met the study's inclusion and exclusion criteria. hsCRP levels were tested in all patients
within 48 hours of admission. Data was entered into a Microsoft Excel database
prospectively.
Results: The average age of the patients in the study was 59.12 years. Eighty-eight
percent of the patients were between the ages of 40 and 80. Also, values were found to
be higher in haemorrhagic stroke (value) than ischemic stroke (value), with a significant
difference. In both types of stroke, there was a significant association between hsCRP
levels and GCS, with lower GCS scores linked with greater hsCRP levels.
Conclusion: We concluded that hsCRP levels are elevated in both ischemic and
hemorrhagic strokes, implying an inflammatory response in acute stroke. Increased
hsCRP levels were linked to the degree of the neurological impairment and a worse
prognosis.