European Journal of Molecular & Clinical Medicine

Introduction: Elevation of serum ferritin levels can result in major health issues. Increased oxidative
stress, inflammation, and endothelial damage are all linked to elevated serum ferritin levels, which in
turn raises the risk of hypertension.
Aim: Serum ferritin levels in patients with high blood pressure and a healthy control group were
measured and compared in this study.
Material and Methods: The present study was a hospital-based observational and analytical study. The
study was conducted over a period of 1 year on 60 patients. The study group comprised of 30 patients
(not diagnosed with hypertension or on any treatment) and the control group comprised of 30 (age and
gender matched) individuals. The levels of serum ferritin were analysed by the chemiluminescent
method.
Result: The results of the present study showed that, the mean value of serum ferritin was 313.17 ±
173.86 ng/ml in study group and 169.50 ± 105.66 ng/ml in control group. The mean SBP was 137.53 ±
14.32 mm/Hg in study group and 121.60 ± 8.09 mm/Hg in control group. The mean DBP was 87.73 ±
8.83 mm/Hg in study group and 71.03 ± 9.56 mm/Hg in control group. The results of the present study
indicate that the difference between the mean serum ferritin and mean SBP, mean DBP among the study
group and control group was found to be significant statistically (p=<0.005).
Conclusion: The current study found a positive association between the mean serum ferritin levels and
high blood pressure among the study participants

Introduction: The autonomic nervous system is key to balance a human activity within
aphysiological condition. But exaggerated sympathetic response increases metabolic
function.Daily stress also plays an important role in activating sympathetic activity, but
chronic stressdysfunctions sympathetic activity and has diverse pathophysiological
consequences.
Aim:Thisresearch was planned to see the impact of stressors on sympathetic activity
inIndian youngadults.
Methods and Methodology: This cross-sectional study was done in the Department
ofPhysiology, of TMMC and RC,Moradabad for a period of six months(July –
December2017) after the clearance from ethical & college research committee, Healthy
young adults(N = 140) aged 18–25 years were enrolled for this study after receiving
written consent. Eighty-six male subjects were in Group -1 having normal BMI (18.5-
24.9kg/m2) and fifty- fourmales were enrolled in Group-2 having BMI (>25kg/m2).
Their BMI was calculated bythequetelet index(kg/m2). after taking individuals height in
meters and weight in kilogram.Basal systolic blood pressure and diastolic blood
pressure were measured by aneroidsphygmomanometer and heart rate were calculated
from lead II of ECG. These parameterswere again observed after inducing stress by
Cold pressure test (CPT), bicycle ergometer, andVideo Game (VG).
Results: There was no significant difference obtained in cardiovascular activity (Heart
rate,Systolic & Diastolic blood pressure) at the baseline position (>0.05) but just after
inducingstress (CPT, ergometer, VG) the sympathetic activity was more noticed in
Group-2 withhighly significant difference(<0.01) Most significant difference was found
after the physicalstressor (ergometer) in heart rate, systolic and diastolic blood pressure
(<0.001). After theCPT significant difference was found in heart rate, systolic blood
pressure (<0.05) diastolicblood pressure (<0.001). Post mental stress (VG) there was
significant difference in heart rateand systolic blood pressure (<0.05) and diastolic
blood pressure (<0.001).
Conclusion: The sympathetic activity was maximum in Group-2 individuals with
highlysignificant difference (<0.01), so they are more prone to hypertension.As a result,
Group 2 isadvised to take precautionary measures by following healthy lifestyle