Keywords : diffusion weighted
To Assess The Role of Diffusion Weighted Magnetic Resonance Imaging in Differentiating Benign From Malignant Prostate Lesions With Histopathological Correlation
European Journal of Molecular & Clinical Medicine,
2021, Volume 8, Issue 4, Pages 2713-2719
Background&Method: This is a prospective study conducted in the Department of Radio
Diagnosis, Index medical college hospital and research centre. 50 patients suspicion of prostatic
pathologies were included in the study. A sample size of 50 was selected using purposive
sampling technique.All the 50 patients were subjected for the multi-parametric MRI sequences
including T1 and T2 weighted anatomical imaging, functional imaging using diffusion weighted
MRI with ADC value calculation.The machine used in this study is GE SIGNA
EXPLORER 1.5 Tesla MRI with phased array body coil.
Result:Majority of lesions 37 (74%) on diffusion weighted imaging were hyperintense
while 13 (26%) were hypointense. Out of 37 hyperintense lesions 24 (92.31%) were
malignant on histopathology and 13 (54.16%) were benign on histopathology. 13 (26%)
lesions appeared hypointense on diffusion weighted imaging 2 (7.69%) were malignant on
histopathology while 11 (45.83%) lesions were benign on histopathology.
This indicated benign lesions tends to both hyperintense and hypointense on diffusion
weighted imaging, benign lesions those appeared hyperintense on diffusion weighted
imaging had inflammatory properties ,that was confirmed on histopathology. Malignant
lesions tends to be hyperintense on diffusion weighted imaging.