European Journal of Molecular & Clinical Medicine

Aim- To observe recurrence rate after conjunctival limbal autograft (CLAU) and tocorrelate
this with preoperative histopathological and morphologicalcharacteristics of pterygium.
Design: Interventional, Prospective, Hospital-Based Study.
Methods: 107 patients with primary pterygium were examined, managed by CLAU and
histopathology sample sent. The outcomes were assessed in terms of clinically significant or
insignificant recurrence till 6 months follow-up.
Results: 57% patients were female. 17.8% participants had Stockers Line and all patients
having stocker’s line had stationary type of pterygium. Fuchs spots were seen in 4.7% of
patients. Histopathology findings includeEpithelial Hyperplasia (80.4%), Vascularity
Overwhelms Fibrosis (39.1%), Vascularity Similar to Fibrosis (28.3%), Fibrosis Overwhelms
Vascularity (34.8%), Perivascular Stromal Inflammation (54.3%), Diffuse Stromal
Inflammation (37.0%). The following variables were significantly associated (p<0.05) with
the Recurrence: Age, Fuchs Spots, higher vascularity and Diffuse Stromal Inflammation on
histopathology.
Conclusion: Factors such as younger age group,higher redness and thickness of pterygium,
Fuchs Spots, higher vascularity and diffuseinflammation on histopathological examination
can be considered as a risk factor for recurrence. However, occupation, laterality, location
and type of pterygiumwere found not to be related to recurrence.

Introduction: Pterygium is one of the very common ophthalmic disorders with an unknown etiology and pathogenesis. Growth of pterygium into the cornea can result in visual impairment, astigmatism, loss of corneal transparency, visual axis obstruction.
Materials and methods: This cross sectional study was done on 500 patients, where demographic details was taken from all the patients including living environment, status, time outdoors, familial history, drug abuse, history of smoking, type of work and education, use of glasses. All of them underwent regular ophthalmic examinations including systemic and comprehensive examination as well as refraction.
Results: The prevalence of Pterygium was 12.6%. 35.6% of the patients were females and 64.4% were males. 51.2% belonged to the 30-39 year age group. 33.3% were farmers and 54% were manual labourers, 61.9%) of the patients had passed their high school while 28.6% were illiterate, 73% had no familial history of pterygium, 61.9% were regular smokers and 25.4% were occasional smokers. 36.5% of the patients had hypertension and 25.4% were obese.
Conclusion: Pterygium formation in our geographical area is quite high and the most common risk factor is exposure to sunlight. Male gender, hypertension and smoking also appear to be associated risk factors. Use of sunglasses may help in reduction of the prevalence of Pterygium.

Background:To compare the efficiency and safety of fibrin glue and suturing technique
for adherence of conjunctival limbal autograft after pterygium excision.
Materials and Methods: AProspectiveinterventional study conducted from September
2018 to December 2020 in the department of Ophthalmology at
KIMS,Narketpally.100eyesof100 patientsoperatedforprimary nasal
pterygium.Autologousconjunctival grafttakenfromthe superotemporal limbu was used
to cover the scleraafter pterygiumexcision.In50 eyes,thetransplantwasattached
tothesclerawitha fibrin tissue adhesive (BeriplastP),in 50 eyeswith10-
0Vicrylsilksutures.Outcome measures included graft position and stability,recurrence
of pterygium, Postoperativepatient discomfort(pain,watering)andbio microscopic
findings(hyperemia,edema).Patientswere followedupatleastforsixmonths.
Results: Subconjunctival haemorrhage occurred underthe graftingonepatientinFibrin
glue group.Granuloma was seen in one patient in suture group,which resolved after
suture removal. Inferior Graft dislodgement was seen in one patient in suture
group.Symptoms like pain, watering, Foreign body sensation were
significantlylessandbiomicroscopicfindingswerebetterin Fibrin glue group.Average
Surgery Cost Was Higher (<0.05)andsurgerytimewasshorter (<0.05)infibrin group.
Conclusion: Fibrin glue is a safe and effective method for attaching conjunctival limbal
autografts.Usingfibringlueforgraft fixation pterygium surgery causes significantly less
postoperative pain,watering,foreign body sensation and
shortenssurgerytimesignificantly.