Online ISSN: 2515-8260

Keywords : Blood pressure


EFFECTS OF INDIVIDUALISED DIALYSATE SODIUM IN HEMODIALYSIS

Dr Kawin Gunasekaran; Dr E Ramprasad Elumalai; Dr M Jayakumar; Dr Manikantan Sekar

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 3177-3194

Sodium is the major extracellular cation in the body and hence and is the major determinant of
extracellular fluid (ECF) content and serum osmolarity . Volume overload contributed by increased
sodium is a major problem in patients on hemodialysis (HD). Sodium entry occurs in hemodialysis
patients from dietary intake, dialysis fluid or from saline infusions given during the hemodialysis session.
Currently, all patients undergoing maintenance hemodialysis in our centre and hospitals world-wide are
dialysed with dialysate sodium of 138 meq/L and this dialysate sodium level used as a standard value in
all patients irrespective of their blood sodium values. Patients undergoing dialysis have an individualized
sodium and osmolarity value which are known as sodium and osmolar set point . respectively, and are
unique for each patient and is highly conserved.
A higher dialysate sodium concentration more than the patient’s plasma sodium level will cause sodium
gain during dialysis and increase the total body sodium. This promotes interdialytic fluid ingestion in
order to restore an individual’s sodium and osmolar set point. These patients might be actually having a
lower sodium set point and if so, with each hemodialysis session, more sodium is continuously being
added to their body, contributing to increased thirst, interdialytic weight gain (IDWG) and blood pressure.
Long standing fluid overload can lead to uncontrolled hypertension, left ventricular hypertrophy and thus,
lead to cardiovascular morbidity and mortality.
Theoretically, it looks advantageous to use tailor made dialysate sodium to avoid addition of excess
sodium to the body during hemodialysis sessions. Several studies have been done regarding the
individualization of sodium prescription in HD patients but the results have been inconsistent. There are
very few studies from India regarding sodium set points in our HD population and by prescribing
Individualized dialysate sodium prescription, co-morbidities mentioned above will be drastically reduced.
Our aim was to investigate and study the beneficial effects of individualized sodium profiling on patients
undergoing dialysis.

Short-Term Sprint Interval Training Improves Systolic and Diastolic Blood Pressure in Sedentary Overweight Women

Norhazira Abdul Rahim; Nor Shazmiera Asyraf Ishak; Nor Aijratul Asikin Mohamad Shalan

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 4048-4057

Sprint Interval Training (SIT) has become one of the time-efficient training protocol which capable to improve fitness and health-related measures in healthy as well in overweight individual. The aim of this study was to determine the effects of short term SIT on body mass index (BMI), total body fat percentage, resting heart rate and blood pressure in overweight sedentary women. Eleven women (aged 20.64 ±0.81 years; body mass index, 30.17 (±3.97) kg/m2) participated in this study. After baseline measurement of BMI, total body fat percentage, resting heart rate and blood pressure, participants completed a 2-week SIT intervention, comprising 6 session of 4 to 6 repeats of 30-second Wingate anaerobic sprints protocol on an electromagnetically braked cycle ergometer, with 4-minute recovery time between each repetition. The BMI, total body fat percentage, resting heart rate and blood pressure assessment were repeated as post-intervention. Significant decrease in systolic pressure (108 ± 9.1 vs 112.36 ± 12.5 mm Hg, P .04) and diastolic pressure (74.45 ± 6.4 vs 79.73 ± 10.5 mm Hg, P .03) were observed after the 2-week SIT intervention. No significant changes were found in BMI, total body fat percentage and resting heart rate. Thus, the 2-week of SIT improves both systolic and diastolic blood pressure in sedentary overweight women, highlighting the potential for this short-term intervention as an alternative exercise programme for the improvement the cardio metabolic health in overweight individual.

THE EFFECTS OF SANDALWOOD AROMATHERAPY (Santalum album) AND BOSSA NOVA MUSIC ON ANXIETY LEVELS OF PEDIATRIC PATIENTS UNDERGOING TOPICAL FLUORIDE TREATMENT

Victor Gradiyanto Mahendra; Ardianti Maartrina Dewi; Udijanto Tedjosasongko; Teguh Budi Wibowo

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 5, Pages 860-865

Background: Anxiety is a condition characterized by strong fear, followed by somatic symptoms that indicate a hyperactive autonomic nervous system. This is a type of emotional disorder that is associated with unexpected and considereddangerous situations. The anxiety of pediatric patients will reduce the treatment success rate. Reducing the anxiety of pediatric patients is very important to increase thetreatment success rate. Purpose: The purpose of this study was to analyze the effect of sandalwood aromatherapy and bossa nova music on the anxiety levels of pediatric patients undergoing dental treatment. Methods: This research was conducted in four groups with four different treatments: the control group, the sandalwood aromatherapy group, the bossa nova music group, and the combination group. Each group consisted of 26 subjects. All 104 patients were treated with topical fluoride treatment for the first time. Blood pressure and pulse measurements asindicators of anxiety were performed twice on each sample, before treatment and after treatment. Blood pressure and pulse were measured with a digital sphygmomanometer. Results: There was a significant enhancement in the difference in blood pressure and pulse in the control group and a significant reduction in the difference in blood pressure and pulse in the other group (p <0.05).Conclusion: Sandalwood aromatherapy and bossa nova music can reduce anxiety levelsin pediatric patients undergoing dental treatment, with the largest reduction in anxiety levels in the group treated with a combination of sandalwood aromatherapy and bossa nova music.

CORRELATION OF RISK FACTORS FOR PREECLAMPSIA WITH BLOOD PRESSURE AND PROTEINURIA

HidayatiRatna .; Hayati Farida; Fuadah Z. Dina; Sari K. Melani; Ludyanti L. Nita; Ishariani Linda

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 5, Pages 1017-1025

Background: Preeclampsia is related to the inability to adapt to the physiological changes of pregnancy that result in decreased maternal organ perfusion. This complex clinical syndrome in preeclampsia can affect all organ systems such as the hemodynamic system, kidney, retina, and blood chemistry, which is manifested by increased blood pressure and protein urine.
Purpose: This study aimed to determine the correlation of the factors causing preeclampsia with blood pressure and protein urine.
Methods: This correlational study using the 127 respondents, sampling purposive sampling techniques, the independent variable factor in preeclampsia (age, genetics, history of diabetes mellitus, history of hypertension), and the independent variable blood pressure and protein urine. The measuring instrument used is a sheet checklist and analyzed by Spearman rank.
Results: The results showed the risk of preeclampsia in the age factor of 40.9% occurred in the 28-35-year-old respondents; 100% of patients had no history/genetic preeclampsia, 100% of respondents did not have a history of diabetes mellitus, and 88.9% did not have a history of hypertension.Systole blood pressure increased moderately and high by 26.0% and 22.0%, while diastolic blood pressure increased moderately and high by 26.0% and 11.0%. Respondents had positive proteinuria of 52%. The results of the analysis are not found a significant correlation between the factors of age, genetics, history of diabetes, and history of hypertension with blood pressure and preeclampsia protein urine on respondents.
Conclusion: History of hypertension associated with blood pressure and proteinuria in preeclampsia. History of hypertension is related to the condition of the blood vessels that manifest hypertension and decreased renal function (protein urine). Therefore, it is recommended in women with a history of hypertension to control blood pressure and perform routine prenatal care during pregnancy to prevent further complications.

Correlation Of Risk Factors For Preeclampsia With Blood Pressure And Proteinuria

Hidayati Ratna; Hayati Farida; Fuadah Z. Dina; Sari K. Melani; Ludyanti L. Nita; Ishariani Linda

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 2, Pages 4710-4717

Background: Preeclampsia is related to the inability to adapt to the physiological changes of pregnancy that result in decreased maternal organ perfusion. This complex clinical syndrome in preeclampsia can affect all organ systems such as the hemodynamic system, kidney, retina, and blood chemistry, which is manifested by increased blood pressure and protein urine.
Purpose: This study aimed to determine the correlation of the factors causing preeclampsia with blood pressure and protein urine.
Methods: This correlational study using the 127 respondents, sampling purposive sampling techniques, the independent variable factor in preeclampsia (age, genetics, history of diabetes mellitus, history of hypertension), and the independent variable blood pressure and protein urine. The measuring instrument used is a sheet checklist and analyzed by Spearman rank.
Results: The results showed the risk of preeclampsia in the age factor of 40.9% occurred in the 28-35-year-old respondents; 100% of patients had no history/genetic preeclampsia, 100% of respondents did not have a history of diabetes mellitus, and 88.9% did not have a history of hypertension. Systole blood pressure increased moderately and high by 26.0% and 22.0%, while diastolic blood pressure increased moderately and high by 26.0% and 11.0%. Respondents had positive proteinuria of 52%. The results of the analysis are not found a significant correlation between the factors of age, genetics, history of diabetes, and history of hypertension with blood pressure and preeclampsia protein urine on respondents.
Conclusion: History of hypertension associated with blood pressure and proteinuria in preeclampsia. History of hypertension is related to the condition of the blood vessels that manifest hypertension and decreased renal function (protein urine). Therefore, it is recommended in women with a history of hypertension to control blood pressure and perform routine prenatal care during pregnancy to prevent further complications.

BLOOD PRESSURE PROFILE IN SCHOOL CHILDREN IN RURAL AND URBAN AREA IN AND AROUND KARAD

D. B. Potdar; Prashnt P. Shah; Naredra P. Porval

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 4168-4174

A cross sectional study among 1000 school going children of age group 6 – 16 years was conducted to study the relation of Blood Pressure with variables Like Body Mass Index, Socio Economic Status, Family History of Hypertension, Age and Sex at our tertiary care hospital Krishna Institute of Medical Sciences Deemed University, Karad. 1.The study group had 100 (10%) children of 13, 14, 15 and 16 years, 90 (9%) children of 6, 8, 9 and 12 years and 80 (8%) children of 7, 10 and 11 years. 12.Systolic hypertension was observed in 13.3% of overweight and 6.7% of obese children. Systolic prehypertension was observed in 11.7% of overweight and 13.3% of obese children. BMI was significantly associated with pre hypertension and hypertension (SBP) in children (p<0.001). Diastolic hypertension was observed in 16.7% of overweight and 6.7% of obese children. Diastolic prehypertension was observed in 18.3% of overweight and 20% of obese children. Only 1.7% and 0.9% of prehypertension and hypertensive children had normal BMI.