Online ISSN: 2515-8260

Keywords : fetal outcome

Role of uterine artery doppler in pregnancy induced hypertension: A prospective study from North India

Dr Farah Nabi, Dr Rafia Aziz, Dr Afak Yusuf Sherwani, Dr Parvaiz Ahmed Shah

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 7, Pages 3109-3116

Background: The triad of pregnancy induced hypertension (PIH), infections, and hemorrhages constitutes a significant proportion in the maternal mortality and morbidity. About 5 to 10 percent of pregnancies are complicated by the PIH. It is being observed that the sensitivity of this screening test is increased in detecting adverse perinatal outcome, if the doppler ultrasound is performed at gestational period of 23 to 26 weeks instead of 19 to 22 weeks. So, present study was conducted with an aim to evaluate the association of the deranged uterine artery velocity indices on doppler ultrasound with maternal and fetal outcomes among pregnant women with PIH.
Methods: The present prospective study was conducted among 132 singleton pregnant women (patient age: 19 to 33 years and gestational age: 25-39 weeks) with PIH in the department of Obstetrics and Gynecology in tertiary care teaching hospital of North India for 12 months (January 2021 to December 2021) after obtaining the ethical approval from the institutional ethical committee.The ultrasound examination was performed using a GENERAL ELECTRIC LOGIQ P5 ultrasound scanner machine.Chi square test was used to find association between uterine artery indices and fetal outcome and a p value of <0.05 was considered as statistically significant.
Results: The mean age of pregnant women was 24.8±3.7 years.In our study 40.8% of subjects were nulliparous, 43.9% of subjects were having parity of 1, 12.2% of subjects were having parity of 2.In our study, the doppler ultrasound was conducted among pregnant women with PIH for various indices. The uterine artery doppler ultrasound showed that 35.7% of subjects were having normal uterine artery indices, whereas 36.7% and 27.6% of subjects were having bilateral abnormal uterine artery indices and unilateral abnormal uterine dopplerrespectively.The chi-square analysis showed statistically significant association between perinatal mortality and abnormal uterine artery indices (p<0.05).
Conclusion: Doppler study for fetal surveillance in pregnancy-induced hypertension is a very useful device and abnormal uterine artery velocimetry also seems to have worse pregnancy outcomes in the present study.

Study of fetomaternal outcome in pregnant women with severe anemia at a tertiary hospital

Pankaj Narayan Baravkar, Tanavi Pankaj Baravkar

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 5, Pages 604-609

Background: Anemia in pregnancy is defined as hemoglobin levels less than 11gm/dL. Severe anaemia is responsible for 20-40% of direct and indirect maternal deaths because of increased susceptibility to cardiac failure, sepsis and association with preeclampsia, antepartum haemorrhage, postpartum haemorrhage and thrombo-embolism. Present study was carried out to fetomaternal outcome in pregnant women with severe anemia at a tertiary hospital.
Material and Methods: Present study was single-center, prospective, observational study, conducted in pregnant women with Hb < 7gm/dL, with gestational age > 28 weeks, delivered at our hospital.
Results: Total 72 women with severe anemia were studied, majority were from 19-25 years age group (52.78 %), mean age was 25.4 ± 3.5 years, had completed primary education (70.83 %), from lower Socio-economic status (84.72 %). Though Un-booked (13.89 %) pregnancies were less than booked cases (86.11 %), majority had less than 4 antenatal visits (75 %). Majority of patients were Para 2 (34.72 %), Para > 2 (31.94 %), had spacing between pregnancy was < 2 years (71.93 %). Vaginal (70.83 %) was most common Mode of delivery, followed by LSCS (26.39 %) & Instrument delivery (2.78 %). In present study, maternal complication/ high risk factors noted were premature delivery (52.78 %), postpartum hemorrhage (34.72 %), preeclampsia (20.83 %), prolonged labor (19.44 %), congestive cardiac failure (16.67 %), puerperal pyrexia (15.28 %).  One maternal mortality (1.39 %) was noted. We noted total 7 deaths (3 Intrauterine fetal death/ Stillbirth & 4 Early neonatal deaths), while Low birth weight (<2500 gm) (65.28 %), NICU admission (48.61 %), Apgar score <7 (at 5 minute) (8.33 %).
Conclusion: Anemia in pregnancy is a major health problem in developing countries. Severe anemia during pregnancy is associated with maternal and fetal health outcomes fetomaternal morbidity and mortality.

A Study on Maternal and Fetal Outcome in Women with Severe Anaemiain Labour

Viplava, Siddula Shireesha, Leela Regalla

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 825-834

Background: In pregnancy, anaemia has a significant impact on the health of fetus as
well as that of mother. It is one of the leading causes responsible for maternal and
perinatal morbidity and mortality. The objectives of the study are to find out the effect
of severe anaemia on women in labour affecting maternal and fetal outcome.
Materials and Methods: This a prospective case control study undertaken in the
Department of Obstetrics and Gynaecology, Govt Maternity Hospital, Petlaburz
attached to Osmania Medical College, Hyderabad. The period of study was from 1st
December 2019 to 31st December 2021.There were a total of 160 study subjects, 80 cases
of severe anaemia (Hb<7gm %) and 80 non anaemic controls (Hb≥ 11gm %).
Results: Low socio economic status (86.25%), inadequate antenatal care (38.75%),
multiparity (71.25%) and no iron supplementation (52.5%) were associated with severe
anaemia cases. Microcytic hypochromic anaemia was more prevalent (76.25%),
suggesting nutritional inadequacies as a cause of anaemia. It was seen that the incidence
of preterm labour (22.5%), atonic PPH (2.5%), sub involution of the uterus (2.5%),
CCF (1.25%), abruptio placentae (1.25%) and maternal mortality (1.25%) was more in
cases of severe anaemia than in the control group. Adverse fetal outcome in the form of
preterm birth (22.5%), low birth weight babies (41.25%), IUGR (13.75%), birth
asphyxia (11.25%), and perinatal mortality (11.25%) was more in the anaemic group
than the controls.