Online ISSN: 2515-8260

Keywords : hepatomegaly


STUDY OF CLINICO-EDIPEMIOLOGICAL PROFILE OF CHILDREN WITH INFANTIILE TREMOR SYNDROME (ITS)

Amit Mathur, Rajendra Babu Mathur, Virendra Kumar Gupta, Jitendra Kumar Gupta, Shikha Gupta, Gaurav Agrawal, Munish Kumar Kakkar, Madhu Mathur

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 9, Pages 639-648

Infantile tremor syndrome (ITS) is a self–limiting disease in infants and young children (5 months to 3 years), most commonly seen in developing countries with poor socio-economic conditions such as Southeast Asia, Indian subcontinent and African countries. Many etiologies have been hypothesized ranging from it being on obscure infection of CNS to being a spectrum of PEM & neurodegenerative diseases
Materials and Methods: This was a cross-sectional and prospective study, Conducted in the department of Paediatrics, Mahatma Gandhi Medical College and Hospital, Jaipur and Department of Paediatrics, Jhalawar Medical College, Jhalawar. A record of clinical profile was made using predesigned proforma after obtaining consent
Results: A total of 50 Children with Infantile Tremor Syndrome enrolled in study, there was male dominancy (72%), Maximum subjects were having age <1 year (76%), exclusive breast feed babies dominate (78%).
Conclusion: Majority of kids were receving improper nutrition in the form of prolonged exclusive nursing without the right complementing foods.

STUDY OF CLINICAL OUTCOME IN ADULT PATIENTS WITH SEROLOGICALLY PROVEN DENGUE SYNDROME AT A TERTIARY HOSPITAL.

Panuganti Raveen, Panuganti Ratnachary, K. Sudharani

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 4, Pages 755-762

Background: Dengue fever is an acute febrile illness (AFI) caused by one or more dengue viruses belonging to genus Flavivirus and transmitted by Aedes aegypti mosquito. The exact clinical and laboratory profile is crucial for early diagnosis and management of patients. Present study was aimed to study clinical outcome in adult patients with serologically proven dengue syndrome at a tertiary hospital.
Material and Methods: Present study was hospital based, observational study, conducted in patients of age > 18 years, of either gender, with acute febrile illness, with serologically proven dengue syndrome admitted in wards & ICUs.
Results: We studied 210 serologically proven dengue patients in present study. Majority of patients were from 31-40 years age group (29.05%), were male (60.48%), NS 1 Positive (81.90%). In present study, non-severe dengue (83.81%) cases were more as compared to severe Dengue fever(DHF) (16.19%). Laboratory findings such as hematocrit < 36%, leukopenia, thrombocytopenia, reactive lymphocytes, prolonged PT, prolonged APPT, SGOT>40 IU/L & SGPT >40 IU/L were common in severe dengue group as compared to non-severe dengue group & difference was statistically significant (p

Radiological profile of dengue among infants at a tertiary care hospital with special reference to increased resistive index of middle cerebral artery: A cross sectional study

Dr Santosh Karpur Dr Anupam Bahe Dr Deepali Vagdalker Dr Mahesh Chander D

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 4, Pages 1594-1604

Background: Ultrasonography is readily available and is non-invasive which gives quick results. It tells about severity of dengue among infants. It is a promising tool. It can help in management and assessing severity of dengue.
Objective: To study radiological profile of dengue among infants with special reference to increased resistive index of middle cerebral artery
Methods: Retrospective study on subjects admitted with infant dengue was done for two years. Data of 98 infants admitted with Dengue were collected from medical records department. Data of infant dengue with congenital heart disease, comorbidities like sepsis and known case primary immunodeficiency were excluded. Radiological findings of ultrasound abdomen & thorax of the subjects were recorded. 

A Study on Observation of Paltelate Status in Malaria

Yerraguntla Shashidhar,Golla Vahini

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 925-934

The present study was conducted in the Department of medicine,Gandhi Hospital,
Secunderabad. 100 malarial fever cases were taken up for the study, which consisted of
79(79%) males and 21% females. Among this, 55% cases were of p.vivax and 45%
p.falciparum. The maximum number of cases fell in the age group of 15-35 years (62%).
100% cases presented with fever, chills and rigors. Other presenting symptoms were
headache (25%)and vomiting (33%). Splenomegaly was seen in 32% cases, while
hepatomegaly in 22%, 15% showed pallor and 8%cases had icterus. Complete
hematological tests were done on cases taken for study and analyzed. Anemia ranged
from 6.0 to 15.6gm/dl, leukocyte count varied from 1.8 to 17.7cu/mm. Platelet count was
done on every patient on day 1, 2, and 3.Thrombocytopenia was seen in 31% (31) cases
of p.vivax, 24% of p.falciparum patients. Association of thrombocytopenia and effect of
treatment was completely analyzed in both p.falciparum and p.vivax the effect of
antimalarial drugs on platelet count was observed. On Day 1 platelet count varied
from 15,000 to 1,94,000. On Day 2 platelet count varied from 14,000 to 1,84,000. On Day
3 platelet count varied from 26,000 to 1,98,000.

Hydatid cyst of liver: Symptoms and Clinical signs

Dr. Saiyad Jameer Basha T, Dr. Bharatkumar G Bidinahal, Dr. Basavaraj Yenagi

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 2, Pages 2637-2641

The hydatid cyst is unique and localized in the right lobe of the liver in 65%. The most frequent extrahepatic locations are the lungs, the spleen and the peritoneum. Liver (55-70%) is the obvious first site after entry through the gut and passage in the portal circulation. Most cysts tend to be located in the right lobe. Patients presenting with varying gastrointestinal symptoms and signs, and symptoms of space occupying lesions of liver like obstructive jaundice, mass per abdomen, patients with complications due to rupture of hydatid cyst were the study subjects. Tenderness was present in 83.3% of patients. Hepatomegaly was present in 33.3%.