Online ISSN: 2515-8260

Keywords : rate of granulation tissue

A Comparative Study of the Efficacy of Topical HydrogelDressings and Conventional Dressings Inchronic Wounds

Pranay Kumar E, Ramprakash Chitimalla, Pala Anand Kumar

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 2419-2427

Background:This study compared the efficacy of topical Hydrogel wound dressings with that of a control group using conventional wound dressings in the healing of chronic ulcers. The primary outcomes measured were the number of ulcers not healed in either group, the amount of non-viable tissue, the rate of granulation tissue formation as percentage of ulcer surface area, and the length of time spent in hospital.
Materials and Methods: A prospective, parallel group, comparative trial design was used in this study. Patients with chronic wounds were admitted to the general surgery department of the Government Medical College in Suryapet. After determining whether or not the participants were willing to receive topical hydrogel dressing, the entire sample population was separated into two equal and comparable groups of 120 patients. Those who refused to participate were exposed to traditional wound dressings, and this group served as the control group. They were then divided into two equal groups of 60 patients each, one for those with diabetes and one for those who did not, based on whether they had diabetes.
Results: As a result, the entire study population was separated into four categories. The purposive sample strategy was used to choose the patients for the study. Patients were followed up on, and the state of their ulcers was determined using a visual score.When compared to the control group, the test group shows significant reduction in slough as early as the third week. The frequency of patients with 75-100 percent wound filled with granulation tissue was higher in the test group as early as the third week compared to the control group, which took more than four weeks to achieve the same result. The number of patients who underwent secondary suturing, skin grafts, and flaps is much higher in the test group than in the control group, and this difference can be seen as early as the third week.
Conclusion: Hydrogel is an excellent topical applicant for the reduction of slough, the promotion of granulation tissue development, and the reepitheilization of wounds, as well as the decrease of hospitalisation time for patients with wounds. When compared to standard treatment with local antiseptics, this results in speedier wound bed preparation for healing, suturing, skin transplant and flap placement and healing.