Online ISSN: 2515-8260

Keywords : meconium aspiration syndrome


Clinical study of etiology & immediate outcome of acute poisoning in children at a tertiary hospital

Nishad Yashawant Patil, Rajendrakumar Hiralal Bedmutha

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 7, Pages 4066-4071

Background: Respiratory distress (RD) is a challenging problem and is one of the most common causes of admission in neonatal intensive care unit (NICU). The common causes of RD in neonates includes transient tachypnea of the newborn (TTN), hyaline membrane disease (HMD), birth asphyxia, pneumonia, meconium aspiration syndrome (MAS), and other miscellaneous causes.Present study was aimed to clinical profile of neonates admitted in NICU with respiratory distress in a tertiary care hospital.
Material and Methods: This study was prospective, observational study, conducted in neonates admitted to NICU with respiratory distress.
Results: In present study, majority neonates were male (56.38 %), had birth weight 1.5 – 2.5 kg (46.28 %), were term gestational age (41.49 %) & delivered vaginally (52.13 %). Symptoms and signs of respiratory distress noted were tachypnea (86.17 %), flaring of alae nasi (84.04 %), chest in drawing (82.45 %), grunting (47.34 %) & cyanosis (42.55 %). Premature rupture of membranes (13.83 %), meconium‑stained amniotic fluid (11.17 %), hypertension (9.04 %), maternal pyrexia (5.85 %), foul smelling liquor (2.66 %) & diabetes mellitus (2.13 %) were maternal risk factors observed among neonates with respiratory distress. Among neonates admitted with respiratory distress common diagnosis were transient tachypnea of newborn (34.57 %), sepsis (20.74 %), respiratory distress syndrome (11.17 %), meconium aspiration syndrome (9.04 %), hyaline membrane disease (8.51 %) & birth asphyxia (5.85 %). Majority neonates were discharged uneventfully (86.71 %) & mortality was observed among 16 neonates (8.51 %).
Conclusion: Common diagnosis observed in neonates with respiratory distress were transient tachypnea of newborn, sepsis, respiratory distress syndrome, meconium aspiration syndrome, hyaline membrane disease & birth asphyxia.

Prospective observational study of outcome of meconium stained amniotic fluid in newborn

Dr. Hardik R Parmar, Dr. Pankti D Desai, Dr. Sunil C Chand, Dr. Harsha M Makwana, Dr. Naresh C Rathva

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 2, Pages 1179-1186

Background: The presence of meconium stained amniotic fluid (MSAF) is a serious sign of fetal compromise, which is associated with an increase in perinatal morbidity, clear amniotic fluid on the other hand is considered reassuring. A study by Mathews and Warshaw found that in 98.4% of cases with meconium stained liquor, the neonates were admitted to the neonatal intensive care units, these were delivered at 37 weeks of gestational age or later as it shows maturation of autonomic nervous system. MSAF occurs in 10% of pregnancies with most occurring at term or particularly post term. The purpose of this study was to evaluate the effect of clear liquor and meconium stained liquor on time and mode of delivery and to find out neonatal morbidity and mortality associated with meconium stained amniotic fluid.
Aim: To correlate the maternal and neonatal factors contributing to morbidly related to Meconium stained amniotic fluid.