Online ISSN: 2515-8260

Keywords : PIH

A Clinical Study of Maternalandperinatal Outcome in Pregnancy Induced Hypertension

Himabindu Sangabathula, Neelima V, Siddareddy Yashovardhini

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 4767-4777

Background:Hypertension is a prevalent and serious disorder that can cause or
exacerbate many health issues. Blood pressure is directly associated to cardiovascular
disease and mortality. Stroke, MI, angina, heart failure, renal failure, and
cardiovascular mortality are all linked to BP. As a result, hypertension is often referred
to as "the silent killer." The study's aim is to assess maternal morbidity and mortality
in pregnant women with pregnancy-induced hypertension. Birth weight, Apgar score,
NICU admission, prenatal morbidity and mortality.
Materials and Methods: During two years, pregnant women aged 21 to 40 weeks were
studied at Govt Medical College &Hospital Nalgonda (July 2019-July 2021). An 80-
patient study. The institutional ethics committee review board approved. Each patient
had a comprehensive history, clinical examination, and proforma. In all instances, the
length of hospital stay, patient recovery, perinatal outcome (birth weight, Apgar score,
NICU admission), and perinatal morbidity and mortality were examined.
Results: he present investigation found that unbooked cases had more severe
preclampsia and eclampsia. Preeclampsia patients who had not had routine prenatal
care were 40 percent unbooked. Unbooked cases have increased maternal and perinatal
mortality. In this study, 40% of NICU admissions were due to LBW/asphyxia. Overall,
50% of newborns were born underweight. PIH was a prominent cause of iatrogenic
premature birth.
Conclusion: 100% registration of pregnant women and good quality antenatal
treatment including weight, blood pressure, and urine analysis with adequate referral
mechanism to tertiary care centres.All family physicians and medical officers need to be
advised to follow a standard management protocol in a case of preeclampsia and
eclampsia with an awareness for prompt referral of women who require to be managed
by specialist. Every tertiary care centre must have specialised expertise. Though PIH is
not preventable, adequate ANC care can slow its progression and timely intervention
can significantly improve perinatal outcomes.

Role Of Serum Calcium As A Predictive Factor In Pregnancy Induced Hypertension

Dr Anita Singh, Dr Jyoti Sengar, Dr Mamta Jadon, Dr Sonam Gupta

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 5107-5114

Aim: To compare serum calcium status in pregnant women with and without PIH.
Material and method:It was a hospital based prospective observational study conducted
in the department of Obstetric and Gynecology, National Capital Region Institute of
Medical Sciences, Meerut for a period of 12 months. 200 antenatal cases after 20 weeks
pregnancy having age between 18-40 years were divided into 2 types based on BP i.e.
Cases-100 patients of PIH (Pregnancy induced hypertension) and Control- 100
normotensive patients. A detailed family and medical history of all the childbearing
women with gestational age 20 weeks or more admitted with the features of HDP
(hypertension disorder of pregnancy) was recorded followed by a thorough clinical
examination. Systolic and diastolic blood pressure of all the participants was carefully
recorded every four hourly. Serum calcium levels were measured by the O- Cresol
PhthaleinComplexone (OCPC) method.
Results: Mean SBP in case and control group was 152.30±10.45 and 118.20±7.66
respectively. Mean DBP in case and control group was 99.42±7.29 and 75.82±5.21
respectively. Hence SBP and DBP was higher in case group as compared to control
group. According to Pearson correlation analysis, negative significant correlation was
found between BP and serum calcium(mg/dL) i.e. with increase in BP, there is decrease
in serum calcium(mg/dL).
Conclusion:The present study emphasizes the need of monitoring serumcalcium during
antenatal period and appropriatemeasures may reduce the incidence of PIH.In areas
where dietary calcium intake is low,calcium supplementation during pregnancy (atdoses
of 1.5–2.0 g elemental calcium/day) isrecommended for the prevention of PIH in all
women, but especially those athigh risk of developing PIH.