Online ISSN: 2515-8260

Keywords : ground glass opacity


Study of High-Resolution Computed Tomography Findings in Covid -19

Prashanth Chikkahonnaiah, Varshini J., Abdullah K. K., Suhail Azham Khan,Sanjay P.

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 4778-4787

Background:Coronavirus Disease 2019 (COVID-19) is caused by a novel corona virus
called SARS-CoV. Reverse transcription–polymerase chain reaction (RT-PCR) test
remains the reference standard to make a definitive diagnosis. However few COVID-19
patients with pulmonary involvement on computed tomography have negative results of
RT-PCR, owing to limitation of nucleic acid detection technologies, sampling errors and
low virus load. Therefore, the aim of this study was to analyse the key features of HRCT
imaging in patients with COVID 19. Aims and objectives: To study various HRCT
findings in COVID 19 patients.
Materials and Methods: A descriptive study was done from January 2021 to June 2021
at department of Respiratory medicine at tertiary care hospital in Mysore. The study
included 100 patients who were laboratory confirmed cases of Covid 19 and who were
subjected to HRCT chest as per guidelines.
Results: In our study, we found that, 24 (24%) patients had 0 lobe involvement and the
rest 75 (75%) had at least one lobe being involved. 48 (48%) patients had all 5 lobes
involved. Of the 76 patients, who had abnormality in HRCT, showed sub pleural 48
(63.1%) involvement, Centro parenchymal involvement in 2 (2.6%), both were involved
in 26 (34.2%).The most common pattern being GGOs with or without consolidation
with a total distribution of (71%), other findings included to be interseptal thickening
[22%], pure consolidation with air bronchogram [8%], nodular thickening [3%],
cavities [3%].
Conclusion: Presence of GGO with or without consolidation should be considered as a
strong suspicion of COVID 19 and patients be treated accordingly.

ROLE OF HRCT CHEST AS PRIMARY INVESTIGATION TO SCREEN SYMPTOMATIC PRIMARY CONTACTS OF COVID-19

Dr Rakesh Gujjar, Dr Hemant Kumar, Dr Himani Mavi, Dr Neha Bidhuri

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 11430-11435

Background: Chest diagnostic imaging has a primary relevance in the diagnosis and severity assessment of COVID-19 together with clinical manifestations. The present study was conducted to assess HRCT chest to screen symptomatic primary contacts of COVID-19.
Materials & Methods: 48symptomatic primary contacts ofCOVID 19 patientsof both genders were enrolled. All underwent both chest CT imaging and laboratory virus nucleic acid test (RT-PCR assay with Nasopharyngeal swab samples).
Results: Out of 48 patients, males were 28 and females were 20. Breathlessness was present in 12, cough in 32, fever in 26, diarrhoea in 7, sore throat in 13, bronchial asthma in 8 and diabetes in 4 cases. The difference was significant (P< 0.05). The time interval between chest CT scan and RT PCR assay was 2.1 days. Results of RT PCR assay was positive        in 30 days and negative in 18 days. Chest CT showed consistent with viral pneumonia (positive) in 40 cases and no CT findings of viral pneumonia in 8 cases. It showed consolidation in 12, ground glass opacityin 24 and reticulation/thickened interlobular septa in 4 cases. The difference was significant (P< 0.05).
Conclusion: Chest CT should be considered for the COVID-19 screening, symptomatic primary contacts of COVID 19 in epidemic areas particularly where access to RT PCR testing is difficult.