Keywords : assisted reproductive technology (ART)
An observational assessment of AMH as a predictive marker of ovarian response in assisted reproductive technology outcome
European Journal of Molecular & Clinical Medicine,
2022, Volume 9, Issue 2, Pages 1397-1403
Objective: To evaluate AMH as a predictive marker of ovarian response in assisted reproductive technology outcome. Methods: 70 women (age 25-40 years) selected for in vitro fertilization treatment were included in this study. Analysis of day-2 serum samples was done for the AMH, FSH, Inhibin B, and LH by ELISA kit methods. USG was done for the antral follicle count (AFC) and oocytes’ retrieval. Results: The mean AMH levels of all treated patients were 2.260 ± 0.417. ROC for AMH indicating poor ovarian response with sensitivity of 72% and specificity of 70%. A statistically significant positive correlation was observed between the number of oocytes retrieved and the AMH (r = 0.620, p = 0.0001) (Fig. 2). Significant correlation was also seen between the number of oocytes retrieved and AFC (r = 0.400, p = 0.0001). Conclusion: Our data demonstrated that AMH is an adequate predictor of both high and poor ovarian response but it does not associate with pregnancy outcomes.