European Journal of Molecular & Clinical Medicine

Introduction: Failure in achieving the coronal marginal integrity could possibly
questions the prognosis of the endodontically treated teeth. The success and the aim of
an endodontic therapy tends to reduce infection in the root canal system and to
eliminate reinfection from the apical and coronal region.
Materials and Methodology: A total of 80 freshly extracted, intact human mandibular
premolars were selected and being used for this study. 40 samples were irrigated with 2
mL of 3% sodium hypochlorite and 17% EDTA, finally rinsed with saline. For another
40 samples irrigation regimen was 2 ml of 3% sodium hypochlorite and tublicid plus,
finally rinsed with saline. Coronal section of 4 mm length was used in this study which
was further obtained by sectioning tooth horizontally with diamond disk. All the
samples were prepared so that they have a through and through channel and were
coated superficially with three layers of nail varnish and were then autoclaved. Each
group comprising of 40 samples were again sub grouped into two such that each has 20
teeth (n=20) and restored with nanocomposite and nano glass ionomer cement based on
the manufacturer protocols.
Results: Sample was irrigated with EDTA and further restored with nanocomposite
demonstrated maximum leakage with mean number of days at which leakage occurred
was 55.82 and least microleakage was seen with samples that were irrigated with
tublicid plus and restored with nanocomposite with mean number of days at which
leakage observed was at 71.32.
Conclusion: To conclude that no material could possibly replace lost tooth structure.
Either the irrigants or the restorative materials may not effectively prevent
microleakage. Therefore, from this study, definitive treatment like crown placement
should be done without any delay in order to achieve a good prognosis of the endodontic
treatment. Failing to do so could result in a fatal prognosis and outcome of the
endodontically treated teeth.