European Journal of Molecular & Clinical Medicine

Introduction: The most important attributes of female body which makes it possible for procreation, is menstrual cycle. In proliferative phase estrogens gradually increase, causing Follicle stimulating harmone and Luteinizing harmone to peak, whereas progesterone remains low throughout. The secretory phase is dominated by the actions of estrogen and progesterone. Reproductive hormones may modulate cardiovascular function through a number of mechanisms.
 Aim of study – To assess the variation in cardiovascular function using recording of pulse and blood pressure indices in different phases of menstrual cycle in females having normal menstrual cycle.
Material And Method – – 50 apparently healthy female aged between 20-25 years were selected for the study and pulse and blood pressure was recorded using automatic blood pressure monitor during the different phase of menstrual cycle as follows: a)Menstrual phase(MP) (2nd day) b)follicular phase(PP) (11th day) c) secretory phase(SP) (22nd day).
Results – After statistical analysis (paired t-test) the finding of study was decrease in systolic BP and mean BP during follicular phase as compared to menstrual phase. But there was significant decrease in diastolic BP and mean BP during secretory phase as compared to menstrual phase. Though there was no significant difference in pulse rate but significant change in pulse pressure between follicular and secretory phase has been shown in present study.
Conclusion – The effect of endogenous change in hormonal which are the physiological changes during different phases of menstrual cycle supports the result of study

Background: Pulse pressure (PP) is an independent predictor of cardiovascular disease microalbuminuria in non-diabetic people. Reduced circadian blood pressure (BP) variation has been identified as a risk factor for diabetic complications. In a sample of type 2 diabetic patients, we looked at the relationship between retinopathy, nephropathy, macrovascular disease, PP, and diurnal BP change.
Method: We performed a 24-hour ambulatory blood pressure (AMBP) and fundoscopy on 100 type 2 diabetes patients, and urine albumin excretion was measured using the urinary albumin / creatinine ratio. It was determined whether or not macrovascular disease existed.