Online ISSN: 2515-8260

Keywords : LSV

Clinical Study of Primary Vericose Veins and its Complications

Azaharuddin Mohammad, Vikram Reddy G

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 1245-1252

Background: Varicose veins are the most common chronic vascular disorders requiring
surgical treatment at one stage or other. Though considerable advances in
understanding of venous patho physiology and modern imaging techniques have
revolutionized the concept of management of varicosity of lower limb, the treatment of
primary varicose veins still remain unsatisfactory. Objectives of the Study: To study the
clinical signs & symptoms of the patients admitted for varicose veins. To study the
prevalence of varicose veins in the patients admitted to Govt Medical College &
Hospital, Suryapet, To study the age & sex distribution, To study the complications of
varicose veins, To evaluate & manage the varicose veins & its complications, To study
the outcome of surgery.
Materials and Methods: A prospective follow up study was undertaken for 40 patients
who were admitted for various symptoms of varicose vein during August 2012 to
August 2014. They were subjected to detailed history taking and examination with
relevant investigations including Doppler venous study and were subjected to
treatment. They were followed up to assess long-term morbidity and late complications.
Results: Total 40 patients admitted for varicose veins admitted during the period from
Aug 2020 to Aug 2021 were studied. Out of 40 patients studied, 24 (60%) patients were
agriculturists, who admitted of having been exposed to prolonged hours of standing
.Among the 40 cases studied, 57 limbs showed varicose veins, of which 32limbs had long
saphenous vein and communicating system involvement (64%). 20 limbs had long
saphenous vein involvement (40%) alone. Among 32 limbs with long saphenous
and communicating system involvement, 45 had pain (90%), 12 had edema (24%), 29
had disfigurement (58%), 14 ulcers (28%). Of the 46 limbs that underwent surgery 26
(52%) underwent saphenofemoral flush ligation with stripping of LSV and subfascial
ligation of perforators & 10 (20%) underwent saphenofemoral flush ligation alone.
Conclusion: Definite relationship exists between occupation involving prolonged
standing and primary varicose veins. The involvement of long saphenous and
communicating system together is commonest followed by long saphenous involvement
alone. Patients with involvement of long saphenous and communicating system or long
saphenous and short saphenous system were more symptomatic than others
Complications of varicose veins were responded well to operative treatment. Results of
surgical treatment are good.

Development, Analysis and Evaluation of Arsenic (III) Sensor

Hema. R; Sundararajan M

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 4, Pages 2533-2551

Pollution or contamination plays a major part in dreadful health hazards. Water, the most essential entity for life is being consumed without the knowledge of contaminants. Arsenic (As III) above 10μg/L is regarded to be poisonous to life and causes lung or skin cancer and cardiovascular geotaxis, mutagenic &carcinogenic effects. Contamination of As may not only occurs in under or drinking water but also in sea water which may be a health threat to aquatic lives. Arsenic decontamination need to be strictly adopted upon any form of water purification. A special technique for the determination by express sensing of arsenic ionic level in water was examined on a Smooth or Glassy carbon electrode (GCE) with nano Gold transformation in 0.5 M H2SO4. The nano Gold was setup using a cycling potential continuously ranging from 0.619 to-0.481 V (vs. HAuCl4.3H2O) Chloro Auric Acid in 0.5 M H2SO4 solution. The Gold nano particles are electro- deposited on GCE. The electrode was examined by Differential Pulse Voltammetry (DPV), Anodic Stripping Voltammetry (ASV), Linear Sweep Voltammetry (LSV) and cyclic Voltammetry (CV). After optimization, a LOD (Level Of Detection) of 0.9 parts per billion (ppb) was achieved with a 60s transformation at -0.94 V in 0.5 M H2SO4whereas the WHO’s (World Health Organization) maximum allowable arsenic level is 10 ppb, in drinking water. Mercury Mercurious Sulphate (MMS) was used as standard reference electrode. The developed sensor was evaluated for copper ion interference and was found to have no interfering effect due to ionic copper which is the most potential obstructing ionic species in ionic arsenic determination.