Online ISSN: 2515-8260

Keywords : Clinical Features


A Study on Outcome of Anterior Cervical Approach in Cervical Compressive Myelopathy

K. Indu Sekhar, Banka Ravi Kumar

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 10003-10012

Background:The aim of our study is to, Analyze the incidence, pathophysiology, clinical
features and various treatment options for cervical compressive myelopathy.Predicting
the surgical outcome in anterior cervical approach in cervical compressive myelopathy.
Materials and Methods: The present study is a prospective study comprising of 90 cases
of cervical spondylotic myelopathy. Studied over a period from September 2013 to
December 2015 in the department of neurosurgery, RMC, GGH, Kakinada. The cases
included in this study were cases of cervical spondylotic myelopathy with ventral
compression or 2 or 3 level of PIVD.
Results: The youngest patient in our study was 18 years old, whereas the eldest patient
was 70 years old. The mean age in our study was 45.7 years. The commonest clinical
presentation in our study was motor symptoms. Out of 46 grade I and II (mild) cases,
86.95% (40 cases) (10 cases) had improvement and 13.04% were remained as such
after1 month Of surgery. In moderate cases (grade III and IV) 70% cases improved,
27.5% cases remained static & 2.5%(1 case) developed Ml in post op period. In 4 severe
cases, 2 cases remained as such whereas 2 cases expired on 2ndpost operative day
because of myocardial infarction. Patients who are operated for single level lesion
showed 100% improvement after 6months followed by 2 level lesion it showed an
improvement of 74% after 6 months and 3 level lesions With 56% after 6months.
Conclusion: In cervical spondylotic myelopathy with anterior compression,
decompression by posterior surgery is ineffective as you can’t remove osteophytes more
over multilevel cervical spondylotic myelopathy is accompanied by various levels of
nerve root compression and posterior surgery is ineffective for the decompression of
nerve roots resulting in persistence of post operative symptoms.

ORAL LICHEN PLANUS – A RETROSPECTIVE CLINICAL STUDY IN A TERTIARY CARE CENTRE

Ch. Rama Mohan, M. Nagaswetha, S.Praveen Kumar, B. Sankar Kumar, Ch.Sudha Rani, G. Narasimha Rao Netha

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 11126-11137

Background:Oral lichen planus (OLP) is a chronic inflammatory disorder with a
relatively high prevalence varying from 0.9 % to 1.2%. It may be confined to oral
cavity or associated with the skin, nails and other mucosal sites. Oral lesions are
chronic, rarely undergo spontaneous remission and are often a source of morbidity.
OBJECTIVE - To investigate the epidemiological and clinical characteristics of oral
lichen planus (OLP) in a group of patients.
Materials and Methods: This is retrospective study done at Gandhi Hospital from 2017
to 2019. A total of 64 lichen planus patients with oral involvement were included. OLP
is diagnosed based on the morphology and associated lesions on the skin, nails or other
mucosa. A biopsy was done in doubtful cases.
Results: Out of 64 studied patients females(41) outnumbered males(23) .The common
age group was 30-60yrs. Isolated OLP was observed in 42%, with cutaneous LP 50%,
with nail involvement 3%, and with genital mucosa 4 %. Buccal mucosa is the
commonest site (84%) followed by tongue 28% and lip 20%. LP involving the lower lip
with actinic changes 5(39%) and pigmentation in 8(61%). The common patterns
observed were reticular 65.6%, erosive 11% and pigmented 11%. Other associations
were submucosal fibrosis in 6, diabetes 10, hypothyroidism 4, vitiligo 1, retro-positive 4,
HCV in 2.
Conclusion: In our study reticular pattern involving the buccal mucosa was the
commonest. Our study showed that LP involving the lower lip was mimicking actinic
cheilitis which may be differentiated. Association of LP with HCV was seen in only in
3.1 % of cases. Regular follow-up was needed for erosive or ulcerative and atrophic LP.