Online ISSN: 2515-8260

Keywords : review


AN EXTENSIVE REVIEW ON INTRICACIES OF AUTISM SPECTRUM DISORDER AND ASSOCIATED PHARMACOLOGICAL ACTIVITY OF CENTELLA ASIATICA

Anamika P. K; Dr. P. Muralidharan

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 2, Pages 662-679

A comprehensive study is undertakenon the functional development of brain in Autism Spectrum Disorder (ASD).Brain functionality trajectories are unique in autism spectrum disorder .Autism spectrum disorder (ASD) is a set of neuro developmental disorders characterized by a deficit in social behaviors and nonverbal interactions such as reduced eye contact, facial expression, and body gestures in the early childhood days till the age of three. It is not necessarily a single disorder, and it is broadly considered to be a multiple disorder resulting from genetic and non-genetic parameters and their interpretation. Hereditary study of ASD has acknowledged mutations that interfere with typical neurodevelopment in womb through childhood. These DNA complexities of genes have been involved in synaptogenesis and axon motility. Recent developments in neuroimaging studies have proved many vital perceptions in vivo into the pathological changes which occur in the patients’ brain with ASD. Amygdala plays a majorrole in the limbic system and the affective loop of the cortico-striato-thalamo-cortical circuit, in cognition and ASD has been proved invarious neuropathological and neuroimaging research findings. Besides the amygdala, the nucleus accumbent is also considered as the vital ingredient which is related with the social recognition response in ASD. Although educational and behavioral treatments have been the mainstay of the management of ASD, pharmacological and interventional treatments have also shown remarkable benefits in subjects with ASD. Also, there have been implications on few patients who experienced through one of the interventional treatments resulted improvement after deep brain stimulation. The key architecture of ASD development which could be the focus for intervention is still an untapped destination. Further work is needed to explore the horizons on the grey trajectories on ASD.

Quality of crystallization of colloidal nanoparticles

Amani Alruwaili

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 11, Pages 4004-4020

This paper undertook a systematic review on the methodological studies on the processes and quality of crystallisation of colloidal nanoparticles. Google Scholar database search using the topic itself as the search term yielded 25 usable papers. The review revealed the existence of innumerable methods for the production of equally varied types of colloidal nanoparticles and the effects of these on the outcomes in terms of quality of crystallisation was evident. Many options appear to be available for anyone to mass produce these particles for any of the numerous commercial uses. However, the selection of the most suitable method has been rendered difficult by the multiplicity of methods and outcomes. The implication of this study is that there is a need for research to identify optimal methods for production of colloidal nanoparticles for targeted commercial uses.

Oro Facial Orofacial Space Infections in Medically Compromised Patients- A Systematic Review & Meta Analysis

Dr. Akshay Mishra; Dr. Vikram V Khare; Dr. Mohammed Muzammil Khan; Dr. Puneeta Vohra; Dr. Jayendra Purohit; Dr. Anil Budumuru

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 11, Pages 6509-6521

Introduction: This study reviews our understanding with Orofacial space infections requiring surgical intervention, including cervical necrotizing fasciitis in medically compromised patients. The purpose of the study was to recognize predisposing and aggravating factors of the disease and identify the possible factors that can lead to life-threatening complications and slow down the healing process

WRITING OVERVIEW OF CORONAVIRUS (COVID- 19) AND CONCLUSION UTILIZING RFO CLASSIFIER

Yogesh Mishra; Sk Hasane Ahammad

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 4, Pages 2609-2414

Mankind's history is watching an abnormal time battling an imperceptible foe; the novel COVID-19 coronavirus. At first, I saw in the Wuhan area of China, presently fastly spreading the world over. SARS-CoV-2 is a new virus responsible for an outbreak of respiratory illness known as COVID-19, which has spread to several countries around the world. There is no specific treatment for disease caused by a novel coronavirus. However, many of the symptoms can be treated and therefore, treatment based on the patient's clinical condition. The specific manifestations incorporate fever, hack, weariness, pneumonia, migraine, the runs, hemoptysis, and dyspnea. Preventive estimates, aimed at example, covers, hand cleanliness rehearses, evasion of open contact, case identification, contact following, then isolates remain compelling aimed at diminishing the transmission. Until this point in time, no particular antiviral treatment is demonstrated powerful. Thus, contaminated individuals principally depend on symptomatic treatment and substantial consideration. Even though these investigations had significance towards control an open crisis, more research should be led to give significant & dependable approaches to deal with this sort of general wellbeing crisis in both short-and long haul.

Systamatic Review On Treatment Of Coronavirus

Dr.Eswari V; Dr.Maunika M

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 7, Pages 5571-5575

Coronavirus-2 (SARS-CoV-2) causes extreme acute respiratory syndrome (SARS) and vascular injury, micro-angiopathy, angiogenesis and widespread thrombosis. The first symptom of the common cold is upper respiratory tract infection. Currently, there is no precise cure for the SARS-CoV-2 infection. COVID-19 reviews numerous prescription drugs used in global economy, which includes antiviral agents, inflammation suppressants, low molecular weight heparins, plasma, and hyperimmune immune globulins. Clinical researchers are using and investigating various ways of handling the virus. This article explores SARS-CoV-2 drug therapy along with other prescription medicines. The article will do the review of the literature done by the authors about the treatment of the coronavirus.

Systamatic Review On Depression During Covid-19

Ms. Siji mol; Dr.Monisha S

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 7, Pages 5551-5560

In 2020, millions of cases of COVID-19 have been detected all over the world. Different infectious diseases are very frightening as of they can lead to death. According to the World Health Organization (WHO), COVID-19 was a virus that a sick person couldn't fight and infect the healthy ones in a short amount of time. WHO has established recommendations, such as isolation, avoiding close contact, caring for oneself and others, keeping updated about the symptoms and risk, recommending appropriate actions, to contain the infection1. The current study is evaluation of the literature done on the depression during the COVID-19 Pandemic. Scopus database have been used for the selection of the articles. Total 1612 articles have been evaluated for the systamatic review

A Review Study On Relationship Among Covid-19 And Pneumonia

Dr.Akila K; Dr.Senthil Nathan

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 7, Pages 5476-5480

First declared as a coronavirus disease by the World Health Organisation (WHO) in March 2020 (COVID-19), the number of Positive and death cases continues to rise even seven months after that. Seven months later. This global pandemic has had a huge effect on the world's health, social and economic facets. Therefore, it is necessary to recognise the risk factors that lead to the production of serious infections for risk stratification, to improve the re-allocation of hospital resources and to direct guidelines and strategies on public health. A variety of co-morbidity consequences such as hypertension, diabetes, dyslipidemia, anaemia, coronary, thyroid disease, and pulmonary disease have been shown to be correlated with serious COVID-19 findings 1. Persons with dementia are the most fragile in normal times as they rely on others for their daily life. In a recent review, dementia has been found to increase the risk of morbidity and death, including incidence of respiratory illness, of hospitalising patients. Unfortunately, until now, no research has shown specifically how dementia is linked to COVID-19. This paper seeks to investigate the theoretically related implications of COVID-19 infection with dementia.