Online ISSN: 2515-8260

Keywords : idiopathic pulmonary fibrosis


To study the role of HRCT & flexible fiberoptic bronchoscopy in diagnosis of interstitial lung disease

Dr. Rahaman Tanzil, Dr. Srikanth Ravoori, Dr. Md. Mateenuddin Saleem

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 4, Pages 3458-3466

Background: High-resolution computed tomography (HRCT) is more sensitive than plain chest radiograph in distinction of ILD (affectability more conspicuous than 90%) and the image illustration of parenchymal peculiarities on HRCT consistently propose a particular course of action of scientific abnormalities.
Aim: To assess the usefulness of HRCT chest and flexible optic bronchoscopy concerning Bronchoalveolar lavage cellular analysis in the diagnosis of interstitial lung disease. Materials and Methods: A prospective observational study was conducted at tertiary hospital in south India. 50 patients who are suspected to have interstitial lung infection by clinical assessment and history with manifestations and signs are assessed with HRCT chest and HRCT affirmed patients are exposed to fiber optic bronchoscopy and bronchoalveolar lavage is performed and their cytological profiles are investigated.
Results: The mean age of the patients was 50.18 years (SD ±14.3), with an age range from 18 to 70years and most of the study subjects were males. Dyspnoea was the most common presenting symptom (90% of patients), followed by cough (84%) and least is dysphagia (6%). In one young female, a cystic pattern was seen on HRCT with multiple diffuse thin-walled cysts which made us to make a diagnosis of LAM.
Conclusion:Thus, HRCT and BAL when combined, help us in making a confident diagnosis of ILD, obviating the need of a lung biopsy which is not feasible in routine practice due to lack of expertise, facilities and patient reluctance in undergoing a biopsy procedure.

Prevalence of Depression and Anxiety in Patients with Idiopathic Pulmonary Fibrosis

Tejinder Singh,Neelam Rathi, Raman Baliyan, Anurag Timothy

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 10541-10546

Background:Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, diffuse
interstitial lung disease of unknown cause that occurs primarily in older adults. Several
causes for IPF have been proposed, including diabetes mellitus, smoking, metal
particles, and sawdust. IPF is the commonest and most severe form of idiopathic
interstitial pneumonia. No curative medical treatment is available for IPF, and lung
transplantation remains the only effective treatment. Psychiatric comorbidities are
common in patients of IPF. Among them, depression and anxiety are more common.
Aim and objective: To study the prevalence of depression and anxiety in patients with
Idiopathic Pulmonary Fibrosis.
Materials and Methods: A total of 50 patients of Idiopathic Pulmonary Fibrosis who
visited Chest and TB OPD were recruited in the study. They were assessed in detail for
the presence of depression and anxiety with the help of the Hamilton Depression and
Anxiety rating scale.
Results: A total of 30(60%) patients out of 50 have comorbid depression and anxiety.
Conclusion: Depression and Anxiety were found to be a common problem in patients
with Idiopathic Pulmonary Fibrosis. A proper address of this issue is important for
management, better outcome, and policymaking in patients with Idiopathic Pulmonary
Fibrosis.