Online ISSN: 2515-8260

Keywords : Hippocampalsparing

Hippocampal sparing in radiation therapy to primary brain tumors - and impact on memory function in adults

Dr.Veda Varshne D Nath, Dr.Geeta S.N, Dr.SalmanKhurshid Shah, Dr.BhaskarVishwanathan, Dr.Richa Tiwari, Dr. Sowmya Narayan, Dr.Shubham Gupta, Dr.KashyapMalleshappa, Dr. Natasha Laishram

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 4, Pages 70-81

Introduction - Sparing the hippocampus during cranial irradiation poses important technical
challenges with respect to contouring and treatment planning.Purpose of this study was to assess
if sparing the hippocampaus region during the planning of radiotherapy using IMRT technique
without compromising the dose conformity to tumour, and to compare memory function of
patient, before the start of irradiation and retention after radiation therapy in both the arms using
the Hopkins verbal learning test.
Materials and Methods -Patients presenting with Primary brain tumours were chosen for the
study. Age 18 to 65 years, diagnosis as per WHO Grading, ECOG performance status {0-2}
were selected. All the types of Primary brain tumours were included.