Online ISSN: 2515-8260

Keywords : ODT ondansetron can be used to prevent post operative nausea and vomiting

Efficacy of orally disintegrating tablet of ondansetron 4mg sublingually compared to ondasetron 4mg intravenousin the management of post-operative nausea and vomiting in patients undergoing elective laparoscopic surgeries under general anesthesia: A non-inferiority study

Dr. Leelavathi Bikumalla, Dr. Swathi Appagalla, Dr. Rajitha Suragouni, Dr. Sarada Devi Vankayalapati, Dr. Surender Pasupuleti

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 4, Pages 544-551

Background: Orally disintegrating tablet (ODT) of ondansetronis an attractive option for
prevention and management of post-operative nausea and vomiting (PONV) compared to
intravenous ondansetron. It is given sub-lingually and automatically gets dissolved and hence
convenient. There is no need of water and hence it does not interfere with the fasting status of
the patients. As it is absorbed by oral mucosa, its bioavailability is high. This is unique thing
about ODT of ondansetronand hence attracts its use.